Antimicrobial and antioxidant properties of spray dried Murraya koenigii leaf powder

The study was directed to analyse the influence of spray drying on antioxidant and antimicrobial activities of Murraya koenigii leaf powder. Tray dried (S1) and spray dried (S3) M. koenigii leaf powder was analysed for various antioxidant and antimicrobial activities. Spray dried powder (S3) exhibited highest DPPH scavenging `activity (90.67%) in comparison to tray dried (S1) powder (66.81) at 1 mg/mL. S1 showed inhibition concentration (IC50) of 1.86 mg/mL for reducing 50% of hydroxyl radicals whereas S3 resulted in IC50 value of 5.02 mg/mL to inhibit the peroxide free radicals. S3 exhibited higher superoxide chelating activity (74%) and iron chelating activity (32.33%) in comparison to S1. S3 was found to be more efficient against pathogenic bacteria (such as Yersinia enterocolitica, Klebsiella pneumonia, Enterococcus faecalis, Pseudomonas aeruginosa) and yeast (Candida albicans) with the inhibition zone of 20, 17, 12, 14, 17 mm respectively.