Effects of Glycine Receptors of the Medial Preoptic Nucleus on Sexual Behavior of Male Wistar Rats

被引:0
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作者
Z. D. Zhuravleva
M. A. Mogutina
I. V. Mukhina
M. Ya. Druzin
机构
[1] National Research N. I. Lobachevsky State University of Nizhny Novgorod,Laboratory of Fundamental and Applied Imaging
[2] Ministry of Health of the Russian Federation,Central Research Laboratory, Privolzhsky (Volga region) Research Medical University
[3] Umeå University,Department of Integrative Medical Biology
关键词
glycine receptors; sexual behavior; hypothalamus;
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摘要
We studied the effect of bilateral microinjections of selective pharmacological agents modulating glycine receptor activity into the medial preoptic nucleus on sexual behavior of male Wistar rats. Application of the glycine receptor blocker strychnine (20 μM, 2 μl) led to a significant inhibition of both appetitive and consummatory components of sexual behavior, whereas stimulation with glycine (1 mM and 50 μM, 2 μl) had no significant effect.
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页码:299 / 301
页数:2
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