Peroxisome proliferator-activated receptors γ/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus

被引：0
|
作者：
Yao-Chung Chuang
Tsu-Kung Lin
Hsuan-Ying Huang
Wen-Neng Chang
Chia-Wei Liou
Shang-Der Chen
Alice YW Chang
Samuel HH Chan
机构：
[1] Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine,Department of Neurology
[2] Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine,Center for Translational Research in Biomedical Sciences
[3] Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine,Department of Pathology
来源：
Journal of Neuroinflammation | / 9卷
关键词：
Status epilepticus; Mitochondrial uncoupling protein 2; Peroxisome proliferator-activated receptors γ; Hippocampal neuronal cell death; Oxidative stress;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 15 条
  • [1] Peroxisome proliferator-activated receptors γ/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus
    Chuang, Yao-Chung
    Lin, Tsu-Kung
    Huang, Hsuan-Ying
    Chang, Wen-Neng
    Liou, Chia-Wei
    Chen, Shang-Der
    Chang, Alice Y. W.
    Chan, Samuel H. H.
    [J]. JOURNAL OF NEUROINFLAMMATION, 2012, 9
  • [2] Resveratrol Promotes Mitochondrial Biogenesis and Protects against Seizure-Induced Neuronal Cell Damage in the Hippocampus Following Status Epilepticus by Activation of the PGC-1 Signaling Pathway
    Chuang, Yao-Chung
    Chen, Shang-Der
    Hsu, Chung-Yao
    Chen, Shu-Fang
    Chen, Nai-Ching
    Jou, Shuo-Bin
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (04):
  • [3] Sirtuin 1 Regulates Mitochondrial Biogenesis and Provides an Endogenous Neuroprotective Mechanism Against Seizure-Induced Neuronal Cell Death in the Hippocampus Following Status Epilepticus
    Chuang, Yao-Chung
    Chen, Shang-Der
    Jou, Shuo-Bin
    Lin, Tsu-Kung
    Chen, Shu-Fang
    Chen, Nai-Ching
    Hsu, Chung-Yao
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (14)
  • [4] Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity
    Patterson, Andrew D.
    Shah, Yatrik M.
    Matsubara, Tsutomu
    Krausz, Kristopher W.
    Gonzalez, Frank J.
    [J]. HEPATOLOGY, 2012, 56 (01) : 281 - 290
  • [5] Heat shock protein 70 protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus via inhibition of nuclear factor-κB activation-induced nitric oxide synthase II expression
    Chang, Chiung-Chih
    Chen, Shang-Der
    Lin, Tsu-Kung
    Chang, Wen-Neng
    Liou, Chia-Wei
    Chang, Alice Y. W.
    Chan, Samuel H. H.
    Chuang, Yao-Chung
    [J]. NEUROBIOLOGY OF DISEASE, 2014, 62 : 241 - 249
  • [6] Peroxisome Proliferator-Activated Receptor γ Coactivator 1α Activates Vascular Endothelial Growth Factor That Protects Against Neuronal Cell Death Following Status Epilepticus through PI3K/AKT and MEK/ERK Signaling
    Huang, Jyun-Bin
    Hsu, Shih-Pin
    Pan, Hsiu-Yung
    Chen, Shang-Der
    Chen, Shu-Fang
    Lin, Tsu-Kung
    Liu, Xuan-Ping
    Li, Jie-Hau
    Chen, Nai-Ching
    Liou, Chia-Wei
    Hsu, Chung-Yao
    Chuang, Hung-Yi
    Chuang, Yao-Chung
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (19) : 1 - 23
  • [7] Vascular endothelial growth factor is up-regulated after status epilepticus and protects against seizure-induced neuronal loss in hippocampus
    Nicoletti, J. N.
    Shah, S. K.
    McCloskey, D. P.
    Goodman, J. H.
    Elkady, A.
    Atassi, H.
    Hylton, D.
    Rudge, J. S.
    Scharfman, H. E.
    Croll, S. D.
    [J]. NEUROSCIENCE, 2008, 151 (01) : 232 - 241
  • [8] Activation of cerebral peroxisome proliferator-activated receptors gamma exerts neuroprotection by inhibiting oxidative stress following pilocarpine-induced status epilepticus
    Yu, Xin
    Shao, Xiao-Guany
    Sun, Hong
    Li, Yong-Nan
    Yang, Jun
    Deng, Yan-Chun
    Huang, Yuan-Gui
    [J]. BRAIN RESEARCH, 2008, 1200 : 146 - 158
  • [9] Expression time course and spatial after experimental neuronal cell death distribution of activated caspase-3 status epilepticus:: Contribution of delayed to seizure-induced neuronal injury
    Weise, J
    Engelhorn, T
    Dörfler, A
    Aker, S
    Bähr, M
    Hufnagel, A
    [J]. NEUROBIOLOGY OF DISEASE, 2005, 18 (03) : 582 - 590
  • [10] Peroxisome proliferator-activated receptor-α activation protects against endoplasmic reticulum stress-induced HepG2 cell apoptosis
    Wei-xiang Tang
    Li-kui Wang
    Yi-qiao Wang
    Zhi-jun Zong
    Zhi-xin Gao
    Xue-sheng Liu
    Yu-jun Shen
    Yu-xian Shen
    Yuan-hai Li
    [J]. Molecular and Cellular Biochemistry, 2014, 385 : 179 - 190
12