Defining the ‘exhausted’ T cells that respond to PD1 checkpoint blockade

被引：0
|
作者：
Yvonne Bordon
机构：
[1] Nature Reviews Immunology,
来源：
Nature Reviews Immunology | 2022年 / 22卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
MYB-dependent precursors of exhausted T cells show stem-like properties and mediate the response to PD1 immune checkpoint blockade.
引用
收藏
页码：593 / 593
相关论文
共 50 条
  • [1] Defining the 'exhausted' T cells that respond to PD1 checkpoint blockade
    Bordon, Yvonne
    NATURE REVIEWS IMMUNOLOGY, 2022, 22 (10) : 593 - 593
  • [2] PD1 blockade promotes IFN-γ production by progenitor exhausted PD1-expressing T cells in atherosclerotic plaques
    Mulholland, Megan
    Yu, Yinda
    Lin, Shiying
    Jakobsson, Gabriel
    Schiopu, Alexandru
    Bjorkbacka, Harry
    Lichtman, Andrew H.
    Gistera, Anton
    Engelbertsen, Daniel
    JOURNAL OF IMMUNOLOGY, 2023, 210 (01):
  • [3] Inhibiting the PD1 Immune Checkpoint and the VEGFA Growth Factor Enhances the Cytotoxicity of Exhausted T Cells in Glioblastoma In Vitro
    Madan, Shriya
    Andrzejewska, Anna
    Gulisashvili, David
    Woodworth, Graeme
    Kukuruga, Debra
    Liang, Yajie
    Walczak, Piotr
    Janowski, Miroslaw
    MOLECULAR THERAPY, 2024, 32 (04) : 603 - 603
  • [4] ALL Progression Induces PD1 on T Cells and Blockade of PD1 Enhances Adoptive Immunotherapy
    Burk, Chad R.
    Fix, William
    Qin, Haiying
    Fry, Terry J.
    BLOOD, 2011, 118 (21) : 1110 - 1111
  • [5] PD-1 Immune Checkpoint Blockade and PSGL-1 Inhibition Synergize to Reinvigorate Exhausted T Cells
    Viramontes, Karla M.
    Neubert, Emily N.
    DeRogatis, Julia M.
    Tinoco, Roberto
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [6] Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade
    Palmer, Douglas C.
    Webber, Beau R.
    Patel, Yogin
    Johnson, Matthew J.
    Kariya, Christine M.
    Lahr, Walker S.
    Parkhurst, Maria R.
    Gartner, Jared J.
    Prickett, Todd D.
    Lowery, Frank J.
    Kishton, Rigel J.
    Gurusamy, Devikala
    Franco, Zulmarie
    Vodnala, Suman K.
    Diers, Miechaleen D.
    Wolf, Natalie K.
    Slipek, Nicholas J.
    McKenna, David H.
    Sumstad, Darin
    Viney, Lydia
    Henley, Tom
    Burckstummer, Tilmann
    Baker, Oliver
    Hu, Ying
    Yan, Chunhua
    Meerzaman, Daoud
    Padhan, Kartik
    Lo, Winnie
    Malekzadeh, Parisa
    Jia, Li
    Deniger, Drew C.
    Patel, Shashank J.
    Robbins, Paul F.
    McIvor, R. Scott
    Choudhry, Modassir
    Rosenberg, Steven A.
    Moriarity, Branden S.
    Restifo, Nicholas P.
    MED, 2022, 3 (10): : 682 - +
  • [7] PD-1 immune checkpoint blockade can synergize with PSGL-1 inhibition to reinvigorate exhausted T cells
    Viramontes, Karla M.
    Neubert, Emily N.
    DeRogatis, Julia M.
    Henriquez, Monique
    Tinoco, Roberto
    JOURNAL OF IMMUNOLOGY, 2023, 210 (01):
  • [8] Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade
    Brian C. Miller
    Debattama R. Sen
    Rose Al Abosy
    Kevin Bi
    Yamini V. Virkud
    Martin W. LaFleur
    Kathleen B. Yates
    Ana Lako
    Kristen Felt
    Girish S. Naik
    Michael Manos
    Evisa Gjini
    Juhi R. Kuchroo
    Jeffrey J. Ishizuka
    Jenna L. Collier
    Gabriel K. Griffin
    Seth Maleri
    Dawn E. Comstock
    Sarah A. Weiss
    Flavian D. Brown
    Arpit Panda
    Margaret D. Zimmer
    Robert T. Manguso
    F. Stephen Hodi
    Scott J. Rodig
    Arlene H. Sharpe
    W. Nicholas Haining
    Nature Immunology, 2019, 20 : 326 - 336
  • [9] Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade
    Miller, Brian C.
    Sen, Debattama R.
    Al Abosy, Rose
    Bi, Kevin
    Virkud, Yamini V.
    LaFleur, Martin W.
    Yates, Kathleen B.
    Lako, Ana
    Felt, Kristen
    Naik, Girish S.
    Manos, Michael
    Gjini, Evisa
    Kuchroo, Juhi R.
    Ishizuka, Jeffrey J.
    Collier, Jenna L.
    Griffin, Gabriel K.
    Maleri, Seth
    Comstock, Dawn E.
    Weiss, Sarah A.
    Brown, Flavian D.
    Panda, Arpit
    Zimmer, Margaret D.
    Manguso, Robert T.
    Hodi, F. Stephen
    Rodig, Scott J.
    Sharpe, Arlene H.
    Haining, W. Nicholas
    NATURE IMMUNOLOGY, 2019, 20 (03) : 326 - +
  • [10] TIGIT and PD1 dual checkpoint blockade restores functionality of tumor-infiltrating T cells in hepatocellular carcinoma
    Ge, Zhouhong
    Zhou, Guoying
    Carrascosa, Lucia Campos
    Gausvik, Erik
    Boor, Patrick
    Noordam, Lisanne
    Pan, Qiuwei
    Verheij, Joanne
    Erdmann, Joris
    Doukas, Michael
    IJzermans, Jan
    Kraan, Jaco
    Peppelenbosch, Maikel
    Kwekkeboom, Jaap
    Sprengers, Dave
    JOURNAL OF HEPATOLOGY, 2020, 73 : S637 - S637
12345