Inhibitory effect of PACAP(6–38) on relaxations induced by PACAP, VIP and non-adrenergic, non-cholinergic nerve stimulation in the guinea-pig taenia caeci

被引:0
|
作者
L. Lénárd Jr.
Z. Lázár
R. Benkó
R. Szigeti
Z. Báthori
G.K. Tóth
B. Penke
L. Barthó
机构
[1] Department of Pharmacology and Pharmacotherapy,
[2] University of Pécs Medical School,undefined
[3] H-7643 Pécs,undefined
[4] Hungary,undefined
[5] Department of Medicinal Chemistry,undefined
[6] University of Szeged Medical School,undefined
[7] Szeged,undefined
[8] Hungary,undefined
关键词
Pituitary adenylate cyclase activating polypeptide (PACAP) PACAP antagonist Vasoactive intestinal polypeptide (VIP) VIP antagonist Taenia caeci (guinea pig) Non-adrenergic non-cholinergic (NANC) relaxation;
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摘要
The effect of the pituitary adenylate cyclase activating polypeptide (PACAP) receptor antagonist PACAP(6–38) on the relaxant response to exogenous PACAP, vasoactive intestinal polypeptide (VIP) and non-adrenergic, non-cholinergic (NANC) nerve stimulation was tested in the guinea-pig taenia caeci, in the presence of atropine (10–6 M) and guanethidine (3×10–6 M).
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页码:492 / 497
页数:5
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