Clinical and Immunological Heterogeneity in Japanese Patients with Gain-of-Function Variants in STAT3

被引：0
|
作者：
Kay Tanita
Fumiaki Sakura
Ryusuke Nambu
Miyuki Tsumura
Yusuke Imanaka
Hidenori Ohnishi
Zenichiro Kato
Jie Pan
Akihiro Hoshino
Koji Suzuki
Motoko Yasutomi
Shuichiro Umetsu
Chizuru Okada
Masatoshi Takagi
Kohsuke Imai
Osamu Ohara
Alexo M. Muise
Satoshi Okada
Tomohiro Morio
Hirokazu Kanegane
机构：
[1] Graduate School of Medical and Dental Sciences,Department of Pediatrics and Developmental Biology
[2] Tokyo Medical and Dental University (TMDU),Department of Pediatrics
[3] Hiroshima University Graduate School of Biomedical and Health Sciences,Division of Gastroenterology and Hepatology
[4] Saitama Children’s Medical Center,SickKids Inflammatory Bowel Disease Center
[5] The Hospital for Sick Children,Cell Biology Program, Research Institute
[6] The Hospital for Sick Children,Department of Pediatrics
[7] Gifu University Graduate School of Medicine,Structural Medicine, United Graduate School of Drug Discovery and Medical Information Sciences
[8] Gifu University,Department of Pediatrics, Faculty of Medical Sciences
[9] University of Fukui,Department of Pediatric Hepatology and Gastroenterology
[10] Saiseikai Yokohama-shi Tobu Hospital,Department of Community Pediatrics, Perinatal and Maternal Medicine
[11] Hiroshima Chuodori Children Clinic,Department of Technology Development
[12] Graduate School of Medical and Dental Sciences,Laboratory for Integrative Genomics
[13] Tokyo Medical and Dental University (TMDU),Department of Pediatrics, Institute of Medical Science and Biochemistry
[14] Kazusa DNA Research Institute,Department of Child Health and Development
[15] RIKEN Center for Integrative Medical Sciences,undefined
[16] University of Toronto,undefined
[17] the Hospital for Sick Children,undefined
[18] Graduate School of Medical and Dental Sciences,undefined
[19] Tokyo Medical and Dental University (TMDU),undefined
来源：
Journal of Clinical Immunology | 2021年 / 41卷
关键词：
Signal transducer and activator of transcription 3; gain-of-function; heterogeneity; incomplete penetrance;
D O I：
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学科分类号：
摘要：
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页码：780 / 790
页数：10
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