Circulating angiopoietin-like 4 links proteinuria with hypertriglyceridemia in nephrotic syndrome

被引:0
|
作者
Lionel C Clement
Camille Macé
Carmen Avila-Casado
Jaap A Joles
Sander Kersten
Sumant S Chugh
机构
[1] Glomerular Disease Therapeutics Laboratory,Department of Pathology
[2] University of Alabama at Birmingham,Department of Pathology
[3] Toronto General Hospital,Department of Nephrology and Hypertension
[4] University of Toronto,undefined
[5] Instituto Nacional De Cardiologia,undefined
[6] University Medical Center Utrecht,undefined
[7] Nutrition,undefined
[8] Metabolism and Genomics Group,undefined
[9] Wageningen University,undefined
来源
Nature Medicine | 2014年 / 20卷
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摘要
Nephrotic syndrome is marked by excess of both protein in the urine (proteinuria) and triglycerides in the blood (hypertriglyceridemia). Sumant Chugh and his colleagues now explain these linked pathologies while also suggesting a possible new therapy to treat the proteinuria without aggravating the hypertriglyceridemia.
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页码:37 / 46
页数:9
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