A bioengineered arginine-depleting enzyme as a long-lasting therapeutic agent against cancer

被引：0
|
作者：
Sai-Fung Chung
Chi-Fai Kim
Suet-Ying Tam
Man-Chung Choi
Pui-Kin So
Kwok-Yin Wong
Yun-Chung Leung
Wai-Hung Lo
机构：
[1] The Hong Kong Polytechnic University,Department of Applied Biology and Chemical Technology, Lo Ka Chung Research Centre for Natural Anti
来源：
Applied Microbiology and Biotechnology | 2020年 / 104卷
关键词：
L-Arg; Human arginase I; Site-specific mono-PEGylation; Pharmacodynamics; Divalent metal ions;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：3921 / 3934
页数：13
相关论文
共 50 条
  • [1] A bioengineered arginine-depleting enzyme as a long-lasting therapeutic agent against cancer
    Chung, Sai-Fung
    Kim, Chi-Fai
    Tam, Suet-Ying
    Choi, Man-Chung
    So, Pui-Kin
    Wong, Kwok-Yin
    Leung, Yun-Chung
    Lo, Wai-Hung
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2020, 104 (09) : 3921 - 3934
  • [2] Mono-PEGylation of a Thermostable Arginine-Depleting Enzyme for the Treatment of Lung Cancer
    Chung, Sai-Fung
    Kim, Chi-Fai
    Kwok, Sui-Yi
    Tam, Suet-Ying
    Chen, Yu Wai
    Chong, Hiu-Chi
    Leung, Siu-Lun
    So, Pui-Kin
    Wong, Kwok-Yin
    Leung, Yun-Chung
    Lo, Wai-Hung
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (12) : 1 - 17
  • [3] Designing the Aplysia punctata Arginine-Depleting Enzyme for Tumor Targeting
    Wolkersdorfer, Alena Maria
    Endo, Yuri
    Kehrein, Josef
    Kappus, Maximilian
    Hattori, Sumitto
    Gutmann, Marcus
    Rudel, Thomas
    Caliskan, Neva
    Lu''hmann, Tessa
    Kato, Yoshinori
    Meinel, Lorenz
    MOLECULAR PHARMACEUTICS, 2025, 22 (03) : 1253 - 1261
  • [4] Designing the Aplysia punctata Arginine-Depleting Enzyme for Tumor Targeting
    Wolkersdorfer, Alena Maria
    Endo, Yuri
    Kehrein, Josef
    Kappus, Maximilian
    Hattori, Sumitto
    Gutmann, Marcus
    Rudel, Thomas
    Caliskan, Neva
    Luehmann, Tessa
    Kato, Yoshinori
    Meinel, Lorenz
    MOLECULAR PHARMACEUTICS, 2025,
  • [5] A modified arginine-depleting enzyme NEI-01 inhibits growth of pancreatic cancer cells
    Chow, Jeremy P. H.
    Cai, Yijun
    Chow, Daniel T. L.
    Chung, Steven H. K.
    Chau, Ka-Chun
    Ng, Ka-Ying
    Leung, Oscar M.
    Wong, Raymond M. H.
    Law, Alan W. L.
    Leung, Yu-On
    Kwok, Sui-Yi
    Leung, Yun-chung
    PLOS ONE, 2020, 15 (04):
  • [6] Delivering Long-Lasting Cancer Vaccines
    Potera, Carol
    GENETIC ENGINEERING & BIOTECHNOLOGY NEWS, 2010, 30 (21): : 18 - 19
  • [7] Vatanidipine hydrochloride: a new long-lasting antihypertensive agent
    Matsumura, Y
    Hayashi, K
    EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2001, 10 (01) : 139 - 155
  • [8] Why long-lasting therapeutic changes in the brain need time
    Roth, Gerhard
    PSYCHOTHERAPEUT, 2016, 61 (06): : 455 - 461
  • [9] Evolution and modulation of intracellular calcium release during long-lasting, depleting depolarization in mouse muscle
    Royer, Leandro
    Pouvreau, Sandrine
    Rios, Eduardo
    JOURNAL OF PHYSIOLOGY-LONDON, 2008, 586 (19): : 4609 - 4629
  • [10] Nanovaccines for Advancing Long-Lasting Immunity against Infectious Diseases
    Gao, Xinglong
    Wang, Xinlian
    Li, Shilin
    Saif Ur Rahman, Muhammad
    Xu, Shanshan
    Liu, Ying
    ACS NANO, 2023, 17 (24) : 24514 - 24538
12345