Fe(HSO4)3 as an efficient catalyst for the preparation of 3,4-dihydropyrimidin-2(1H)-ones in solution and under solvent-free conditions

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作者
F. Shirini
M. A. Zolfigol
A. -R. Abri
机构
[1] University of Guilan,Department of Chemistry, College of Science
[2] Bu-Ali Sina University,Faculty of Chemistry
关键词
3,4-Dihydropyrimidin-2(1; )-ones; Solvent-free conditions; Biginelli reaction; Three-component condensation; Fe(HSO; );
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摘要
A one-pot three-component condensation of aromatic aldehydes, β-ketoesters and urea or thiourea, efficiently promoted in the presence of Fe(HSO4)3 in solution and under solvent-free conditions, produced 3,4-dihydropyrimidin-2(1H)-ones. The method offers several advantages including simple, easy and clean work-up procedure, relatively short reaction times and good to high yields of the products
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页码:96 / 99
页数:3
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