Microwave Assisted Synthesis and Antimicrobial Activity of Novel Pyrrolidine Derivatives

被引：0
|
作者：
K. Sreekanth
Anjali Jha
机构：
[1] GIS,Department of Chemistry
[2] GITAM,undefined
来源：
Russian Journal of General Chemistry | 2020年 / 90卷
关键词：
novel pyrrolidine derivatives; characterization; antimicrobial activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Microwave assisted synthesis of 1-acetyl-2-benzylpyrrolidine-2-carboxylic acid and its derivatives has been developed with highly encouraging yields. 2-Benzyl-tert-butylpyrrolidine-1,2-dicarboxylate is used as an initial compound in the four steps synthesis of the target compounds. Structures of the products 5a–5h have been confirmed by spectroscopic methods. According to antimicrobial tests 1-acetyl-2-benzylpyrrolidine-2-carboxamide 5c is determined to be the most potent product.
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页码：129 / 134
页数：5
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