Brain and Testis Accumulation of Regorafenib is Restricted by Breast Cancer Resistance Protein (BCRP/ABCG2) and P-glycoprotein (P-GP/ABCB1)

被引：0
|
作者：
Anita Kort
Selvi Durmus
Rolf W. Sparidans
Els Wagenaar
Jos H. Beijnen
Alfred H. Schinkel
机构：
[1] The Netherlands Cancer Institute,Division of Molecular Oncology
[2] Utrecht University,Division of Pharmacoepidemiology & Clinical Pharmacology Department of Pharmaceutical Sciences, Faculty of Science
[3] The Netherlands Cancer Institute/ Slotervaart Hospital,Department of Pharmacy & Pharmacology
[4] The Netherlands Cancer Institute,Department of Clinical Pharmacology
来源：
Pharmaceutical Research | 2015年 / 32卷
关键词：
ABCB1; ABCG2; brain accumulation; regorafenib; testis accumulation;
D O I：
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学科分类号：
摘要：
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页码：2205 / 2216
页数：11
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