Biomechanical characterisation of a degradable magnesium-based (MgCa0.8) screw

被引:0
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作者
Hazibullah Waizy
Andreas Weizbauer
Matthias Maibaum
Frank Witte
Henning Windhagen
Arne Lucas
Berend Denkena
Andrea Meyer-Lindenberg
Fritz Thorey
机构
[1] Hanover Medical School,Department of Orthopaedic Surgery
[2] Hanover Medical School,Laboratory for Biomechanics and Biomaterials
[3] Institute of Production Engineering and Machine Tools (IFW),Small Animal Clinic
[4] Leibnitz University of Hanover,undefined
[5] An der Universität 2,undefined
[6] School of Veterinary Medicine Hanover,undefined
关键词
Polylactic Acid; Open Circuit Potential; Corrosive Medium; Natural Bone; Synthetic Bone;
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学科分类号
摘要
Magnesium alloys have been in the focus of research in recent years as degradable biomaterial. The purpose of this study was the biomechanical characterisation of MgCa0.8-screws. The maximum pull out force of screws was determined in a synthetic bone without corrosion and after fixed intervals of corrosion: 24, 48, 72 and 96 h. This in vitro study has been carried out with Hank’s solution with a flow rate corresponding to the blood flow in natural bone. A maximum pull out force (Fmax) of 201.5 ± 9.3 N was measured without corrosion. The biomechanical parameter decreased by 30% after 96 h in corrosive medium compared to the non-corrosion group. A maximum load capacity of 28 ± 7.6 N/h was determined. Our biomechanical data suggests that this biodegradable screw provides a promising bone-screw-fixation and has great potential for medical application.
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页码:649 / 655
页数:6
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