A novel highly selective allosteric inhibitor of tyrosine kinase 2 (TYK2) can block inflammation- and autoimmune-related pathways

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作者
Celia X.-J. Chen
Wei Zhang
Shulan Qu
Fucan Xia
Yidong Zhu
Bo Chen
机构
[1] Shanghai Qilu Pharmaceutical R&D Center Limited,Department of Immunology and Inflammation
[2] Present address: China Resources Pharmaceutical Group Limited,undefined
关键词
TYK2; JAK; Cytokine pathway; Pseudokinase regulatory domain; Allosteric inhibitor; Psoriasis; Autoimmune diseases;
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