共 50 条
- [1] A novel highly selective allosteric inhibitor of tyrosine kinase 2 (TYK2) can block inflammation- and autoimmune-related pathwaysCELL COMMUNICATION AND SIGNALING, 2023, 21 (01)Chen, Celia X. -J.论文数: 0 引用数: 0 h-index: 0机构: Shanghai Qilu Pharmaceut R&D Ctr Ltd, Dept Immunol & Inflammat, Shanghai, Peoples R China Shanghai Qilu Pharmaceut R&D Ctr Ltd, Dept Immunol & Inflammat, Shanghai, Peoples R ChinaZhang, Wei论文数: 0 引用数: 0 h-index: 0机构: Shanghai Qilu Pharmaceut R&D Ctr Ltd, Dept Immunol & Inflammat, Shanghai, Peoples R China Shanghai Qilu Pharmaceut R&D Ctr Ltd, Dept Immunol & Inflammat, Shanghai, Peoples R ChinaQu, Shulan论文数: 0 引用数: 0 h-index: 0机构: Shanghai Qilu Pharmaceut R&D Ctr Ltd, Dept Immunol & Inflammat, Shanghai, Peoples R China Shanghai Qilu Pharmaceut R&D Ctr Ltd, Dept Immunol & Inflammat, Shanghai, Peoples R ChinaXia, Fucan论文数: 0 引用数: 0 h-index: 0机构: Shanghai Qilu Pharmaceut R&D Ctr Ltd, Dept Immunol & Inflammat, Shanghai, Peoples R China Shanghai Qilu Pharmaceut R&D Ctr Ltd, Dept Immunol & Inflammat, Shanghai, Peoples R ChinaZhu, Yidong论文数: 0 引用数: 0 h-index: 0机构: Shanghai Qilu Pharmaceut R&D Ctr Ltd, Dept Immunol & Inflammat, Shanghai, Peoples R China Shanghai Qilu Pharmaceut R&D Ctr Ltd, Dept Immunol & Inflammat, Shanghai, Peoples R ChinaChen, Bo论文数: 0 引用数: 0 h-index: 0机构: Shanghai Qilu Pharmaceut R&D Ctr Ltd, Dept Immunol & Inflammat, Shanghai, Peoples R China China Resources Pharmaceut Grp Ltd, Beijing, Peoples R China Shanghai Qilu Pharmaceut R&D Ctr Ltd, Dept Immunol & Inflammat, Shanghai, Peoples R China
- [2] IN-121803, a novel highly selective allosteric inhibitor of tyrosine kinase 2 (TYK2) for the treatment of autoimmune diseaseJOURNAL OF INVESTIGATIVE DERMATOLOGY, 2024, 144 (08) : S95 - S95Chung, H.论文数: 0 引用数: 0 h-index: 0机构: HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South Korea HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South KoreaPark, J.论文数: 0 引用数: 0 h-index: 0机构: HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South Korea HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South KoreaTae, Y.论文数: 0 引用数: 0 h-index: 0机构: HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South Korea HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South KoreaHwang, I.论文数: 0 引用数: 0 h-index: 0机构: HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South Korea HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South KoreaPark, C.论文数: 0 引用数: 0 h-index: 0机构: HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South Korea HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South KoreaKim, J.论文数: 0 引用数: 0 h-index: 0机构: HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South Korea HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South KoreaLee, K.论文数: 0 引用数: 0 h-index: 0机构: HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South Korea HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South KoreaKim, J.论文数: 0 引用数: 0 h-index: 0机构: HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South Korea HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South KoreaKim, D.论文数: 0 引用数: 0 h-index: 0机构: HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South Korea HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South KoreaKim, H.论文数: 0 引用数: 0 h-index: 0机构: HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South Korea HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South KoreaKim, B.论文数: 0 引用数: 0 h-index: 0机构: HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South Korea HK Inno N Corp, Innovat Drug Discovery R&D Inst, Gyeonggi Do, South Korea
- [3] Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165JOURNAL OF MEDICINAL CHEMISTRY, 2019, 62 (20) : 8973 - 8995Wrobleski, Stephen T.论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAMoslin, Ryan论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USALin, Shuqun论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAZhang, Yanlei论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USASpergel, Steven论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAKempson, James论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Dept Discovery Synth, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USATokarski, John S.论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Mol Struct & Design, Mol Discovery Technol, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAStrnad, Joann论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Immunosci Discovery Biol, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAZupa-Fernandez, Adriana论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Immunosci Discovery Biol, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USACheng, Lihong论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Immunosci Discovery Biol, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAShuster, David论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Immunosci Discovery Biol, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAGillooly, Kathleen论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Immunosci Discovery Biol, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAYang, Xiaoxia论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Immunosci Discovery Biol, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAHeimrich, Elizabeth论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Immunosci Discovery Biol, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAMcIntyre, Kim W.论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Immunosci Discovery Biol, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAChaudhry, Charu论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Leads Discovery & Optimizat, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAKhan, Javed论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Mol Struct & Design, Mol Discovery Technol, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USARuzanov, Max论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Mol Struct & Design, Mol Discovery Technol, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USATredup, Jeffrey论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Mol Struct & Design, Mol Discovery Technol, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAMulligan, Dawn论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Mol Struct & Design, Mol Discovery Technol, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAXie, Dianlin论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Mol Struct & Design, Mol Discovery Technol, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USASun, Huadong论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Metab & Pharmacokinet Dept, Pharmaceut Candidate Optimizat, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAHuang, Christine论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Metab & Pharmacokinet Dept, Pharmaceut Candidate Optimizat, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAD'Arienzo, Celia论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Metab & Pharmacokinet Dept, Pharmaceut Candidate Optimizat, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAAranibar, Nelly论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Metab & Pharmacokinet Dept, Pharmaceut Candidate Optimizat, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAChiney, Manoj论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Metab & Pharmacokinet Dept, Pharmaceut Candidate Optimizat, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAChimalakonda, Anjaneya论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Metab & Pharmacokinet Dept, Pharmaceut Candidate Optimizat, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAPitts, William J.论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USALombardo, Louis论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USACarter, Percy H.论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USABurke, James R.论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Immunosci Discovery Biol, POB 4000, Princeton, NJ 08543 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USAWeinstein, David S.论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USA Vividion Therapeut Inc, 5820 Nancy Ridge Dr, San Diego, CA 92121 USA Bristol Myers Squibb Res & Dev, Immunosci Discovery Chem, POB 4000, Princeton, NJ 08543 USA
- [4] Tyrosine Kinase 2 (TYK2) Allosteric Inhibitors To Treat Autoimmune DiseasesJOURNAL OF MEDICINAL CHEMISTRY, 2019, 62 (20) : 8951 - 8952Chang, Yu论文数: 0 引用数: 0 h-index: 0机构: Jinan Univ, Affiliated Hosp 1, Int Cooperat Lab Tradit Chinese Med Modernizat &, MoE, 601 Huangpu Ave, Guangzhou 510632, Guangdong, Peoples R China Jinan Univ, Sch Pharm, 601 Huangpu Ave, Guangzhou 510632, Guangdong, Peoples R China Jinan Univ, Affiliated Hosp 1, Int Cooperat Lab Tradit Chinese Med Modernizat &, MoE, 601 Huangpu Ave, Guangzhou 510632, Guangdong, Peoples R ChinaXu, Shilin论文数: 0 引用数: 0 h-index: 0机构: Chinese Acad Sci, Shanghai Inst Mat Med, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China Jinan Univ, Affiliated Hosp 1, Int Cooperat Lab Tradit Chinese Med Modernizat &, MoE, 601 Huangpu Ave, Guangzhou 510632, Guangdong, Peoples R ChinaDing, Ke论文数: 0 引用数: 0 h-index: 0机构: Jinan Univ, Affiliated Hosp 1, Int Cooperat Lab Tradit Chinese Med Modernizat &, MoE, 601 Huangpu Ave, Guangzhou 510632, Guangdong, Peoples R China Jinan Univ, Sch Pharm, 601 Huangpu Ave, Guangzhou 510632, Guangdong, Peoples R China Jinan Univ, Affiliated Hosp 1, Int Cooperat Lab Tradit Chinese Med Modernizat &, MoE, 601 Huangpu Ave, Guangzhou 510632, Guangdong, Peoples R China
- [5] Targeting the Tyrosine Kinase 2 (TYK2) Pseudokinase Domain: Discovery of the Selective TYK2 Inhibitor ABBV-712JOURNAL OF MEDICINAL CHEMISTRY, 2023, 66 (20) : 14335 - 14356Breinlinger, Eric论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA AbbVie Biores Ctr, Worcester, MA 01605 USAVan Epps, Stacy论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA AbbVie Biores Ctr, Worcester, MA 01605 USAFriedman, Michael论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA AbbVie Biores Ctr, Worcester, MA 01605 USAArgiriadi, Maria论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA AbbVie Biores Ctr, Worcester, MA 01605 USAChien, Ellen论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA AbbVie Biores Ctr, Worcester, MA 01605 USAChhor, Gekleng论文数: 0 引用数: 0 h-index: 0机构: Abbvie Inc, 1 North Waukegan Rd, N Chicago, IL 60064 USA AbbVie Biores Ctr, Worcester, MA 01605 USACowart, Marlon论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USADunstan, Theresa论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA AbbVie Biores Ctr, Worcester, MA 01605 USAGraff, Candace论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA AbbVie Biores Ctr, Worcester, MA 01605 USAHardee, David论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA Abbvie Inc, 1 North Waukegan Rd, N Chicago, IL 60064 USA AbbVie Biores Ctr, Worcester, MA 01605 USAHerold, J. Martin论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA AbbVie Biores Ctr, Worcester, MA 01605 USALittle, Andrew论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA AbbVie Biores Ctr, Worcester, MA 01605 USAMccarthy, Richard论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA AbbVie Biores Ctr, Worcester, MA 01605 USAParmentier, Julie论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA AbbVie Biores Ctr, Worcester, MA 01605 USAPerham, Matthew论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA AbbVie Biores Ctr, Worcester, MA 01605 USAQiu, Wei论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA Abbvie Inc, 1 North Waukegan Rd, N Chicago, IL 60064 USA AbbVie Biores Ctr, Worcester, MA 01605 USASchrimpf, Michael论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA Abbvie Inc, 1 North Waukegan Rd, N Chicago, IL 60064 USA AbbVie Biores Ctr, Worcester, MA 01605 USAVargo, Thomas论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA AbbVie Biores Ctr, Worcester, MA 01605 USAWebster, Matthew P.论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA Abbvie Inc, 1 North Waukegan Rd, N Chicago, IL 60064 USA AbbVie Biores Ctr, Worcester, MA 01605 USAWu, Fei论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA AbbVie Biores Ctr, Worcester, MA 01605 USABennett, Dawn论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA AbbVie Biores Ctr, Worcester, MA 01605 USAEdmunds, Jeremy论文数: 0 引用数: 0 h-index: 0机构: AbbVie Biores Ctr, Worcester, MA 01605 USA AbbVie Biores Ctr, Worcester, MA 01605 USA
- [6] Discovery of a Potent and Subtype-Selective Tyk2 Degrader Based on an Allosteric Tyk2 InhibitorSSRN, 2022,Kato, Jun-Ya论文数: 0 引用数: 0 h-index: 0机构: Synthetic Research Department, ASKA Pharmaceutical Company Limited, 26-1 Muraoka-Higashi 2-Chome, Kanagawa, Fujisawa,251-8555, Japan Synthetic Research Department, ASKA Pharmaceutical Company Limited, 26-1 Muraoka-Higashi 2-Chome, Kanagawa, Fujisawa,251-8555, JapanKorenaga, Shigeru论文数: 0 引用数: 0 h-index: 0机构: Drug Discovery Department, ASKA Pharmaceutical Company Limited, 26-1 Muraoka-Higashi 2-Chome, Kanagawa, Fujisawa,251-8555, Japan Synthetic Research Department, ASKA Pharmaceutical Company Limited, 26-1 Muraoka-Higashi 2-Chome, Kanagawa, Fujisawa,251-8555, JapanIwakura, Masaru论文数: 0 引用数: 0 h-index: 0机构: Synthetic Research Department, ASKA Pharmaceutical Company Limited, 26-1 Muraoka-Higashi 2-Chome, Kanagawa, Fujisawa,251-8555, Japan Synthetic Research Department, ASKA Pharmaceutical Company Limited, 26-1 Muraoka-Higashi 2-Chome, Kanagawa, Fujisawa,251-8555, Japan
- [7] Discovery of a potent and subtype-selective TYK2 degrader based on an allosteric TYK2 inhibitorBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 79Kato, Jun-ya论文数: 0 引用数: 0 h-index: 0机构: ASKA Pharmaceut Co Ltd, Synthet Res Dept, 26-1 Muraoka Higashi 2 Chome, Fujisawa, Kanagawa 2518555, Japan ASKA Pharmaceut Co Ltd, Synthet Res Dept, 26-1 Muraoka Higashi 2 Chome, Fujisawa, Kanagawa 2518555, JapanKorenaga, Shigeru论文数: 0 引用数: 0 h-index: 0机构: ASKA Pharmaceut Co Ltd, Drug Discovery Dept, 26-1 Muraoka Higashi 2 Chome, Fujisawa, Kanagawa 2518555, Japan ASKA Pharmaceut Co Ltd, Synthet Res Dept, 26-1 Muraoka Higashi 2 Chome, Fujisawa, Kanagawa 2518555, JapanIwakura, Masaru论文数: 0 引用数: 0 h-index: 0机构: ASKA Pharmaceut Co Ltd, Synthet Res Dept, 26-1 Muraoka Higashi 2 Chome, Fujisawa, Kanagawa 2518555, Japan ASKA Pharmaceut Co Ltd, Synthet Res Dept, 26-1 Muraoka Higashi 2 Chome, Fujisawa, Kanagawa 2518555, Japan
- [8] Discovery of Tyrosine Kinase 2 (TYK2) Inhibitor (PF-06826647) for the Treatment of Autoimmune DiseasesJOURNAL OF MEDICINAL CHEMISTRY, 2020, 63 (22) : 13561 - 13577Gerstenberger, Brian S.论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Cambridge, MA 02139 USA Pfizer Inc, Groton, CT 06340 USAAmbler, Catherine论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Groton, CT 06340 USA Pfizer Inc, Groton, CT 06340 USAArnold, Eric P.论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Groton, CT 06340 USA Pfizer Inc, Groton, CT 06340 USABanker, Mary-Ellen论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Groton, CT 06340 USA Pfizer Inc, Groton, CT 06340 USABrown, Matthew F.论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Groton, CT 06340 USA Pfizer Inc, Groton, CT 06340 USAClark, James D.论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Cambridge, MA 02139 USA Pfizer Inc, Groton, CT 06340 USADermenci, Alpay论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Groton, CT 06340 USA Pfizer Inc, Groton, CT 06340 USADowty, Martin E.论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Cambridge, MA 02139 USA Pfizer Inc, Groton, CT 06340 USAFensome, Andrew论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Cambridge, MA 02139 USA Pfizer Inc, Groton, CT 06340 USAFish, Susan论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Cambridge, MA 02139 USA Pfizer Inc, Groton, CT 06340 USAHayward, Matthew M.论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Groton, CT 06340 USA Pfizer Inc, Groton, CT 06340 USAHegen, Martin论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Cambridge, MA 02139 USA Pfizer Inc, Groton, CT 06340 USAHollingshead, Brett D.论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Cambridge, MA 02139 USA Pfizer Inc, Groton, CT 06340 USAKnafels, John D.论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Groton, CT 06340 USA Pfizer Inc, Groton, CT 06340 USALin, David W.论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Groton, CT 06340 USA Pfizer Inc, Groton, CT 06340 USALin, Tsung H.论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Cambridge, MA 02139 USA Pfizer Inc, Groton, CT 06340 USAOwen, Dafydd R.论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Cambridge, MA 02139 USA Pfizer Inc, Groton, CT 06340 USASaiah, Eddine论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Cambridge, MA 02139 USA Pfizer Inc, Groton, CT 06340 USASharma, Raman论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Groton, CT 06340 USA Pfizer Inc, Groton, CT 06340 USAVajdos, Felix F.论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Groton, CT 06340 USA Pfizer Inc, Groton, CT 06340 USAXing, Li论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Cambridge, MA 02139 USA Pfizer Inc, Groton, CT 06340 USAYang, Xiaojing论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Groton, CT 06340 USA Pfizer Inc, Groton, CT 06340 USAYang, Xin论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Groton, CT 06340 USA Pfizer Inc, Groton, CT 06340 USAWright, Stephen W.论文数: 0 引用数: 0 h-index: 0机构: Pfizer Inc, Groton, CT 06340 USA Pfizer Inc, Groton, CT 06340 USA
- [9] Selective Tyrosine Kinase 2 (TYK2) Inhibition in Plaque PsoriasisJOURNAL OF DRUGS IN DERMATOLOGY, 2024, 23 (08) : 645 - 652Kircik, Leon论文数: 0 引用数: 0 h-index: 0机构: Icahn Sch Med Mt Sinai, Dept Dermatol, New York, NY 10029 USA Icahn Sch Med Mt Sinai, Dept Dermatol, New York, NY 10029 USAAldredge, Lakshi M.论文数: 0 引用数: 0 h-index: 0机构: VA Portland Healthcare Syst, Dermatol Serv, Portland, OR USA Icahn Sch Med Mt Sinai, Dept Dermatol, New York, NY 10029 USADiRuggiero, Douglas论文数: 0 引用数: 0 h-index: 0机构: Skin Canc & Cosmet Dermatol Ctr, Rome, GA USA Icahn Sch Med Mt Sinai, Dept Dermatol, New York, NY 10029 USA
- [10] Discovery of WD-890: A novel allosteric TYK2 inhibitor for the treatment of multiple autoimmune diseasesBIOMEDICINE & PHARMACOTHERAPY, 2023, 167Fang, Zhiqin论文数: 0 引用数: 0 h-index: 0机构: Cent South Univ, Xiangya Hosp, Hunan Engn Res Ctr Skin Hlth & Dis, Xiangya Clin Res Ctr Canc Immunotherapy,Hunan Key, Changsha, Hunan, Peoples R China Cent South Univ, Xiangya Hosp, Hunan Engn Res Ctr Skin Hlth & Dis, Xiangya Clin Res Ctr Canc Immunotherapy,Hunan Key, Changsha, Hunan, Peoples R ChinaSun, Hongyin论文数: 0 引用数: 0 h-index: 0机构: Southern Med Univ, Sch Pharmaceut Sci, Guangzhou, Guangdong, Peoples R China Southern Med Univ, Affiliated Fengxian Hosp, Shanghai, Peoples R China Cent South Univ, Xiangya Hosp, Hunan Engn Res Ctr Skin Hlth & Dis, Xiangya Clin Res Ctr Canc Immunotherapy,Hunan Key, Changsha, Hunan, Peoples R ChinaWang, Yutong论文数: 0 引用数: 0 h-index: 0机构: Cent South Univ, Xiangya Sch Med, Clin Med Eight Year Program, Changsha, Hunan, Peoples R China Cent South Univ, Xiangya Hosp, Hunan Engn Res Ctr Skin Hlth & Dis, Xiangya Clin Res Ctr Canc Immunotherapy,Hunan Key, Changsha, Hunan, Peoples R ChinaSun, Zhenliang论文数: 0 引用数: 0 h-index: 0机构: Southern Med Univ, Affiliated Fengxian Hosp, Shanghai, Peoples R China Cent South Univ, Xiangya Hosp, Hunan Engn Res Ctr Skin Hlth & Dis, Xiangya Clin Res Ctr Canc Immunotherapy,Hunan Key, Changsha, Hunan, Peoples R ChinaYin, Mingzhu论文数: 0 引用数: 0 h-index: 0机构: Cent South Univ, Xiangya Hosp, Hunan Engn Res Ctr Skin Hlth & Dis, Xiangya Clin Res Ctr Canc Immunotherapy,Hunan Key, Changsha, Hunan, Peoples R China Chongqing Univ, Gorges Hosp 3, Clin Res Ctr CRC, Med Pathol Ctr MPC,Canc Early Detect & Treatment C, Wanzhou, Chongqing, Peoples R China Chongqing Univ, Translat Med Res Ctr TMRC, Sch Med, Shapingba, Chongqing, Peoples R China Cent South Univ, Xiangya Hosp, Hunan Engn Res Ctr Skin Hlth & Dis, Xiangya Clin Res Ctr Canc Immunotherapy,Hunan Key, Changsha, Hunan, Peoples R China