CLL;
R-FC;
standard therapy;
Bendamustin;
first line therapy;
relapse therapy;
D O I:
10.1007/s12254-009-0116-8
中图分类号:
学科分类号:
摘要:
The dominating clinical presentations concerning CLL at this year’s ASH meeting were given on the results of two large randomized phase III trials exploring the use of rituximab (R) in addition to fludarabine and cyclophosphamide (FC). The data of these trials as well as a phase II trial applying R-Bendamustin convincingly demonstrated the clinical benefit of chemoimmunotherapy in CLL, at least for the younger and physically fit patients without del17p.
机构:
IRCCS San Raffaele Hosp, Div Expt Oncol, Dept Oncohaematol, Milan, Italy
Univ Vita Salute San Raffaele, Milan, ItalyIRCCS San Raffaele Hosp, Div Expt Oncol, Dept Oncohaematol, Milan, Italy
Scarfo, Lydia
Ferreri, Andres J. M.
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机构:
IRCCS San Raffaele Hosp, Div Expt Oncol, Dept Oncohaematol, Milan, ItalyIRCCS San Raffaele Hosp, Div Expt Oncol, Dept Oncohaematol, Milan, Italy
Ferreri, Andres J. M.
Ghia, Paolo
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机构:
IRCCS San Raffaele Hosp, Div Expt Oncol, Dept Oncohaematol, Milan, Italy
Univ Vita Salute San Raffaele, Milan, ItalyIRCCS San Raffaele Hosp, Div Expt Oncol, Dept Oncohaematol, Milan, Italy
机构:
Univ Calif San Diego, Moores Canc Ctr, Dept Med, Div Hematol Oncol, 3855 Hlth Sci Dr MC 0820, La Jolla, CA 92093 USAUniv Calif San Diego, Moores Canc Ctr, Dept Med, Div Hematol Oncol, 3855 Hlth Sci Dr MC 0820, La Jolla, CA 92093 USA
Kipps, Thomas J.
Stevenson, Freda K.
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机构:
Univ Southampton, Southampton Canc Res UK Ctr, Fac Med, Southampton, Hants, EnglandUniv Calif San Diego, Moores Canc Ctr, Dept Med, Div Hematol Oncol, 3855 Hlth Sci Dr MC 0820, La Jolla, CA 92093 USA
Stevenson, Freda K.
Wu, Catherine J.
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h-index: 0
机构:
Dana Farber Canc Inst, Boston, MA 02115 USAUniv Calif San Diego, Moores Canc Ctr, Dept Med, Div Hematol Oncol, 3855 Hlth Sci Dr MC 0820, La Jolla, CA 92093 USA
Wu, Catherine J.
Croce, Carlo M.
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h-index: 0
机构:
Ohio State Univ, Dept Mol Virol, Immunol & Med Genet, Columbus, OH 43210 USAUniv Calif San Diego, Moores Canc Ctr, Dept Med, Div Hematol Oncol, 3855 Hlth Sci Dr MC 0820, La Jolla, CA 92093 USA
Croce, Carlo M.
Packham, Graham
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h-index: 0
机构:
Univ Southampton, Southampton Canc Res UK Ctr, Fac Med, Southampton, Hants, EnglandUniv Calif San Diego, Moores Canc Ctr, Dept Med, Div Hematol Oncol, 3855 Hlth Sci Dr MC 0820, La Jolla, CA 92093 USA
Packham, Graham
Wierda, William G.
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h-index: 0
机构:
MD Anderson Canc Ctr, Dept Hematol, 1515 Holcombe Blvd, Houston, TX 77030 USAUniv Calif San Diego, Moores Canc Ctr, Dept Med, Div Hematol Oncol, 3855 Hlth Sci Dr MC 0820, La Jolla, CA 92093 USA
Wierda, William G.
O'Brien, Susan
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif Irvine, Dept Med, Div Hematol, Irvine, CA USAUniv Calif San Diego, Moores Canc Ctr, Dept Med, Div Hematol Oncol, 3855 Hlth Sci Dr MC 0820, La Jolla, CA 92093 USA
O'Brien, Susan
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机构:
Gribben, John
Rai, Kanti
论文数: 0引用数: 0
h-index: 0
机构:
Feinstein Inst Med Res, Northwell Hlth, CLL Res & Treatment Program, New Hyde Pk, New York, NY USAUniv Calif San Diego, Moores Canc Ctr, Dept Med, Div Hematol Oncol, 3855 Hlth Sci Dr MC 0820, La Jolla, CA 92093 USA