A mechanism for value-guided choice based on the excitation-inhibition balance in prefrontal cortex

被引:0
|
作者
Gerhard Jocham
Laurence T Hunt
Jamie Near
Timothy E J Behrens
机构
[1] Oxford Centre for Functional MRI of the Brain (FMRIB Centre),Department of Experimental Psychology
[2] University of Oxford,undefined
[3] John Radcliffe Hospital,undefined
[4] University of Oxford,undefined
[5] Wellcome Trust Centre for Neuroimaging,undefined
[6] University College London,undefined
来源
Nature Neuroscience | 2012年 / 15卷
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摘要
Here the authors show that ventromedial prefrontal cortex (vmPFC) levels of GABA and glutamate in human volunteers are predictive of both behavioral performance and the dynamics of a neural value comparison signal in a manner as predicted by models of decision-making, thus providing evidence for neural competition in vmPFC supporting value-guided choice.
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页码:960 / 961
页数:1
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