HPLC-coupled spectroscopic techniques (UV, MS, NMR) for the structure elucidation of phthalides in Ligusticum chuanxiong

被引：0

作者：

S. Zschocke

I. Klaiber

R. Bauer

B. Vogler

机构：

[1] Universität Hohenheim,Institut für Chemie

[2] Karl-Franzens-Universität Graz,Institut für Pharmakognosie

[3] University of Alabama in Huntsville,Department of Chemistry

来源：

Molecular Diversity | 2005年 / 9卷

关键词：

dereplication; HPLC-MS; HPLC-NMR; HPLC-UV; phthalides; online-coupled spectroscopy;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Ligusticum chuanxiong Hort., a plant that is frequently used in traditional Chinese medicine, has been studied using HPLC-coupled spectroscopic techniques such as HPLC-UV, HPLC-MS as well as HPLC-NMR. With the aid of these modern spectroscopic techniques, the main constituents, namely senkyunolide A, butylphthalide, neocnidilide and Z-ligustilide, have been characterized and identified. Phthalide dimers, present in smaller amounts, have been identified by HPLC-UV and HPLC-MS analysis and compared with reference compounds. Stereochemical features of some phthalide monomers have been determined by detailed spectroscopic studies for the first time.

引用

页码：33 / 39

页数：6

共 20 条

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MOLECULAR DIVERSITY, 2005, 9 (1-3) : 33 - 39
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