IL-17 mediates resistance to anti-VEGF therapy

被引：0
|
作者：
Eleni Maniati
Thorsten Hagemann
机构：
[1] Eleni Maniati and Thorsten Hagemann are at the Centre for Cancer and Inflammation,
[2] Barts Cancer Institute,undefined
[3] Queen Mary University of London,undefined
[4] London,undefined
[5] UK.,undefined
来源：
Nature Medicine | 2013年 / 19卷
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学科分类号：
摘要：
Interleukin-17 (IL-17) released in the tumor microenvironment in response to drugs blocking vascular endothelial growth factor (VEGF) triggers stromal-derived inflammatory and VEGF-independent angiogenic programs that induce the drug refractoriness found in cancers resistant to anti-angiogenic therapy (pages 1114–1123).
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页码：1092 / 1094
页数：2
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