Bioequivalence of Chiral DrugsStereospecific versus Non-Stereospecific Methods

被引：0
|
作者：
Reza Mehvar
Fakhreddin Jamali
机构：
[1] Drake University,College of Pharmacy and Health Sciences
[2] University of Alberta,Faculty of Pharmacy
来源：
Clinical Pharmacokinetics | 1997年 / 33卷
关键词：
Disopyramide; Propafenone; Total Drug; Bioequivalence Study; Tiaprofenic Acid;
D O I：
暂无
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学科分类号：
摘要：
Guidelines for bioequivalence of non-racemic pharmaceuticals are abundant in the literature. However, few guidelines exist for the bioequivalence of racemic drugs which consist of 2 or more stereoisomers. The aim of this article is to address the question of whether the bioequivalence of racemic drugs should be based on the measurement of the individual enantiomers or that of the total drug.
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页码：122 / 141
页数：19
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