Synthesis of 3-Alkyl-5-(diethylaminomethyl)-1-(1,3-thiazol-4-yl)-1H-pyrazoles

被引：0
|
作者：
Karayeva, A. R. [1 ]
Shatirova, M. I. [1 ]
Mamedov, B. A. [1 ]
Nagieva, Sh. F. [1 ]
Gadzhiyeva, L. Ya. [1 ]
机构：
[1] Minist Sci & Educ Azerbaijan, Inst Polymer Mat, Sumgait 5004, Azerbaijan
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 60卷 / 01期
关键词：
pyrazoles; thioureas; 1,3-thiazole; heterocyclization; pharmacophoric groups; ANTIFUNGAL ACTIVITY; DERIVATIVES; ANTIBACTERIAL;
D O I：
10.1134/S1070428024010056
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
3-Alkyl-5-(diethylaminomethyl)pyrazoles reacted with chloroacetyl chloride to give 1-chloroacetyl derivatives which were subjected to heterocyclization with thiobenzamide, thiourea, and N-phenylthiourea in the presence of triethylamine in ethanol. As a result, previously unknown 3-alkyl-5-(diethylaminomethyl)-1-(1,3-thiazol-4-yl)-1H-pyrazoles were synthesized.
引用
收藏
页码：33 / 36
页数：4
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