Doxorubicin plus Ifosfamide as Salvage Treatment for Patients with Advanced Breast Cancer Refractory to Epirubicin plus Cyclophosphamide

被引:0
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作者
Aristidis Polyzos
C. Kosmas
N. Tsavaris
C. Markopoulos
N. Kalahanis
O. Papadopoulos
T. Arnaouti
P. P. Sfikakis
机构
[1] Athens University School of Medicine,First Department of Propaedeutic Medicine
[2] Laikon Hospital,Medical Oncology Unit
[3] Goudi,Department of Pathophysiology
[4] Helena Venizelou Hospital,Department of Surgery
[5] Athens University School of Medicine,undefined
[6] Laikon Hospital,undefined
[7] Athens University School of Medicine,undefined
[8] Laikon Hospital,undefined
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Breast Cancer; Paclitaxel; Doxorubicin; Epirubicin; Advanced Breast Cancer;
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摘要
Objective: To investigate the response and toxicity of a salvage regimen in patients with advanced breast cancer whose tumours became resistant to fluorouracil-epirubicin-cyclophosphamide (FEC). By substituting doxorubicin for epirubicin and ifosfamide for cyclophosphamide, we aimed to evaluate the possible lack of cross-resistance between the two anthracyclines and the two alkylating agents.
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页码:349 / 355
页数:6
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