Trends in the Use of Cardiac Imaging for Women with Newly Diagnosed Breast Cancer

被引:0
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作者
Ana Barac
Claudine Isaacs
Nawar M. Shara
Filipa Lynce
Sameer Desale
Kevin Haynes
Arnold L. Potosky
机构
[1] Georgetown University,MedStar Heart and Vascular Institute
[2] Georgetown University Medical Center,Lombardi Comprehensive Cancer Center
[3] MedStar Health Research Institute,Department of Biostatistics and Biomedical Informatics
[4] HealthCore,undefined
[5] Inc.,undefined
关键词
Cardiovascular imaging; Breast cancer; Cardiotoxicity; Adverse events; Cardiovascular disease; Diagnostic imaging; Chemotherapy; Biological therapy;
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学科分类号
摘要
We investigated time trends and factors associated with the use of cardiac imaging among women with early-stage breast cancer prior to the initiation of treatment. Of 11,732 women ages 24–64, diagnosed with stage I–III breast cancer in 2006–2011, 2550 (22%) received anthracycline-based chemotherapy. Baseline cardiac imaging was used in 79% of patients receiving anthracyclines and increased over time. Of 2277 (20%) women who received non-anthracycline therapy, 16% received cardiac imaging. Women receiving cardiac imaging in non-anthracycline therapy group were more likely to have higher cardiovascular risk, as well as higher cancer stage and worse histological tumor grade suggesting that results of imaging might have influenced the choice of cancer therapy. Our findings indicate the need for cardio-oncology collaboration in identification and treatment of women at high risk for adverse oncology and cardiovascular outcomes.
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页码:478 / 489
页数:11
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