Phosphatidylserine is polarized and required for proper Cdc42 localization and for development of cell polarity

被引:0
|
作者
Gregory D. Fairn
Martin Hermansson
Pentti Somerharju
Sergio Grinstein
机构
[1] Program in Cell Biology,Department of Biochemistry and Developmental Biology
[2] The Hospital for Sick Children,undefined
[3] Institute of Biomedicine,undefined
来源
Nature Cell Biology | 2011年 / 13卷
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摘要
In yeast, polarized localization of Cdc42 is essential for budding and mating, but how polarity is attained has been elusive. Grinstein and colleagues show that phosphatidylserine accumulates in a polar fashion in yeast, and is required for the proper localization of Cdc42.
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页码:1424 / 1430
页数:6
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