Biologically active metabolites of the actinobacterium Streptomyces sp. GW 33/1593

被引：0
|
作者：
M. P. Sobolevskaya
V. A. Denisenko
S. Fotso
H. Laach
N. I. Menzorova
Yu. T. Sibirtsev
T. A. Kuznetsova
机构：
[1] Far-East Branch of the Russian Academy of Sciences,Pacific Institute of Bioorganic Chemistry
[2] University of Göttingen,Department of Organic and Biomolecular Chemistry
来源：
Russian Chemical Bulletin | 2008年 / 57卷
关键词：
terrestrial actinobacteria; cyclo(; -tyrosyl-; -proline); 6-(3-methylbut-2-enyl)isatin; dipeptides; 2,3-dihydroxybenzoic acid; biological activity;
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学科分类号：
摘要：
A new cyclic dipeptide, 3-a[(4-hydroxybenzyl)methyl]hexahydropyrrolo[1,2-a]pyrazine-1,4-dione (1) together with the known compounds, 2,3-dihydroxybenzoic acid (2), and 6-(3-methylbut-2-enyl)isatin (3) were isolated from the actinobacterium Streptomyces sp. GW 33/1593. Compounds 1 and 2 possessed cytotoxic activity against the sea urchin Strongylocentrotus intermedius embryos.
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页码：665 / 668
页数：3
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