Modeling and rescue of defective blood–brain barrier function of induced brain microvascular endothelial cells from childhood cerebral adrenoleukodystrophy patients

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作者
Catherine A. A. Lee
Hannah S. Seo
Anibal G. Armien
Frank S. Bates
Jakub Tolar
Samira M. Azarin
机构
[1] University of Minnesota,Department of Genetics and Cell Development
[2] University of Minnesota,Department of Chemical Engineering and Materials Science
[3] University of Minnesota,Ultrastructural Pathology Unit, Veterinary Diagnostic Laboratory, College of Veterinary Medicine
[4] University of Minnesota,Department of Pediatrics
关键词
Adrenoleukodystrophy; In vitro human blood–brain barrier (BBB) model; Brain microvascular endothelial cells; Trans-endothelial electrical resistance; Human induced pluripotent stem cells (hiPSC); Amphiphilic block copolymers;
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