Systemic Immune Response to Vaccination on FDG-PET/CT

被引：25
|
作者：
Mingos M. [1 ]
Howard S. [1 ]
Giacalone N. [2 ]
Kozono D. [2 ]
Jacene H. [1 ]
机构：
[1] Department of Imaging, Dana-Farber Cancer Institute and Department of Radiology, Brigham and Women’s Hospital, 450 Brookline Avenue, Boston, 02215, MA
[2] Department of Radiation Oncology, Brigham and Women’s Hospital, 75 Francis Street, Boston, 02115, MA
来源：
Nuclear Medicine and Molecular Imaging | 2016年 / 50卷 / 4期
关键词：
FDG; FDG-PET/CT; Immunization; Lung cancer; Spleen; Vaccine;
D O I：
10.1007/s13139-015-0385-6
中图分类号：
学科分类号：
摘要：
A patient with newly diagnosed right lung cancer had transient 18F-fluorodeoxyglucose (FDG)-avid left axillary lymph nodes and intense splenic FDG uptake on positron emission tomography (PET)/computed tomography (CT). History revealed that the patient received a left-sided influenza vaccine 2–3 days before the examination. Although inflammatory FDG uptake in ipsilateral axillary nodes is reported, to our knowledge, this is the first report of visualization of the systemic immune response in the spleen related to the influenza vaccination on FDG-PET/CT. The history, splenic uptake and time course on serial FDG-PET/CT helped to avoid a false-positive interpretation for progressing lung cancer and alteration of the radiation therapy plan. © 2015, Korean Society of Nuclear Medicine.
引用
收藏
页码：358 / 361
页数：3
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