Synthesis of enantiomers of N-(2-aminopurin-6-yl)amino acids

被引：0
|
作者：
V. P. Krasnov
A. Yu. Vigorov
D. A. Gruzdev
G. L. Levit
A. M. Demin
I. A. Nizova
A. A. Tumashov
L. Sh. Sadretdinova
E. B. Gorbunov
V. N. Charushin
机构：
[1] Ural Branch of the Russian Academy of Sciences,I. Ya. Postovsky Institute of Organic Synthesis
来源：
Russian Chemical Bulletin | 2015年 / 64卷
关键词：
purines; amino acids; enantiomers; racemization; high performance liquid chromatography;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Nonracemic N-(2-aminopurin-6-yl)-substituted amino acids were synthesized by nucleophilic substitution of chlorine atom in 2-acetamido-6-chloropurine upon treatment with amino acid tert-butyl esters and subsequent removal of protecting groups. Their enantiomeric composition was determined by HPLC on chiral stationary phases.
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页码：2106 / 2113
页数：7
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