Gamma-radiation dose-rate effects on DNA damage and toxicity in bacterial cells

被引:0
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作者
Jiho Min
Chang Woo Lee
Man Bock Gu
机构
[1] Kwangju Institute of Science and Technology (K-JIST),National Research Laboratory of Environmental Biotechnology
[2] Korea Atomic Energy Research Institute,undefined
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关键词
Dose Rate; Linear Energy Transfer; High Dose Rate; Radiation Dose Rate; Photorhabdus Luminescens;
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摘要
In order to investigate the relationship between radiation dose-rate and bacterial DNA damage as well as general cellular toxicity, two recombinant Escherichia coli strains, DPD2794 and GC2 were used. Following gamma-ray irradiation, these bioluminescent bacteria showed quantitative stress responses in terms of DNA damage and general toxicity depending on the dose rates of energy deposition, i.e. dose-rate of radiation. In addition, an inverse relationship was found, at lower dose rates between 0.5 and 1 Gy/h and a parabolic relationship at dose rates between 0.5 and 2.6 Gy/h.
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页码:189 / 192
页数:3
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