Ethyl pyruvate protects against sepsis-associated encephalopathy through inhibiting the NLRP3 inflammasome

被引:0
|
作者
Xiaoli Zhong
Lingli Xie
Xiaolong Yang
Fang Liang
Yanliang Yang
Jianbin Tong
Yanjun Zhong
Kai Zhao
Yiting Tang
Chuang Yuan
机构
[1] Central South University,Department of Hematology and Critical Care Medicine, The 3rd Xiangya Hospital
[2] Central South University,Department of Pathophysiology, School of Basic Medical Science
[3] Central South University,Department of Physiology, School of Basic Medical Science
[4] Third Xiangya Hospital of Central South University,Department of Anesthesiology
[5] Central South University,ICU Center, The Second Xiangya Hospital
来源
Molecular Medicine | 2020年 / 26卷
关键词
Sepsis-associated encephalopathy; Ethyl pyruvate; NLRP3 inflammasome; Innate immunity; Sepsis;
D O I
暂无
中图分类号
学科分类号
摘要
引用
下载
收藏
相关论文
共 50 条
  • [1] Ethyl pyruvate protects against sepsis-associated encephalopathy through inhibiting the NLRP3 inflammasome
    Zhong, Xiaoli
    Xie, Lingli
    Yang, Xiaolong
    Liang, Fang
    Yang, Yanliang
    Tong, Jianbin
    Zhong, Yanjun
    Zhao, Kai
    Tang, Yiting
    Yuan, Chuang
    MOLECULAR MEDICINE, 2020, 26 (01)
  • [2] Artemisinin protects mice against burn sepsis through inhibiting NLRP3 inflammasome activation
    Long, Huibao
    Xu, Bincan
    Luo, Yanling
    Luo, Keqin
    AMERICAN JOURNAL OF EMERGENCY MEDICINE, 2016, 34 (05): : 772 - 777
  • [3] Breaking the vicious cycle: Targeting the NLRP3 inflammasome for treating sepsis-associated encephalopathy
    Zhong, Hui
    Liu, Tianshu
    Shang, You
    Huang, Chaolin
    Pan, Shangwen
    BIOMEDICINE & PHARMACOTHERAPY, 2024, 177
  • [4] Resveratrol Protects against Sepsis-Associated Encephalopathy and Inhibits the NLRP3/IL-1β Axis in Microglia
    Sui, Da-ming
    Xie, Qun
    Yi, Wen-jing
    Gupta, Sahil
    Yu, Xi-ya
    Li, Jin-bao
    Wang, Jun
    Wang, Jia-feng
    Deng, Xiao-ming
    MEDIATORS OF INFLAMMATION, 2016, 2016
  • [5] Caffeine Citrate Protects Against Sepsis-Associated Encephalopathy and Inhibits the UCP2/NLRP3 Axis in Astrocytes
    Hu, Jing
    Cheng, Yan
    Chen, Ping
    Huang, Zhaoqi
    Yang, Liqi
    JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, 2022, 42 (06): : 267 - 278
  • [6] Ulinastatin protects against sepsis-induced myocardial injury by inhibiting NLRP3 inflammasome activation
    Qiu, Juanjuan
    Xiao, Xiaoguang
    Gao, Xue
    Zhang, Yongli
    MOLECULAR MEDICINE REPORTS, 2021, 24 (04)
  • [7] Hydrogen-rich saline regulates NLRP3 inflammasome activation in sepsis-associated encephalopathy rat model
    Dumbuya, John Sieh
    Chen, Xinxin
    Du, Jiang
    Li, Siqi
    Liang, Lili
    Xie, Hairui
    Zeng, Qiyi
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 123
  • [8] Puerarin protects against sepsis-associated encephalopathy by inhibiting NLRP3/Caspase-1/GSDMD pyroptosis pathway and reducing blood-brain barrier damage
    Zhou, Shuang
    Li, Yuhua
    Hong, Yi
    Zhong, Zhitao
    Zhao, Min
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 945
  • [9] Maf1 Ameliorates Sepsis-Associated Encephalopathy by Suppressing the NF-kB/NLRP3 Inflammasome Signaling Pathway
    Chen, Shenglong
    Tang, Chaogang
    Ding, Hongguang
    Wang, Zhonghua
    Liu, Xinqiang
    Chai, Yunfei
    Jiang, Wenqiang
    Han, Yongli
    Zeng, Hongke
    FRONTIERS IN IMMUNOLOGY, 2020, 11
  • [10] Inhibiting the NLRP3 Inflammasome
    El-Sharkawy, Lina Y.
    Brough, David
    Freeman, Sally
    MOLECULES, 2020, 25 (23):