Rod photoreceptors drive circadian photoentrainment across a wide range of light intensities

被引:0
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作者
Cara M Altimus
Ali D Güler
Nazia M Alam
A Cyrus Arman
Glen T Prusky
Alapakkam P Sampath
Samer Hattar
机构
[1] Johns Hopkins University,Department of Biology
[2] Weill Medical College of Cornell University,Department of Physiology and Biophysics
[3] Zilkha Neurogenetic Institute,Department of Physiology and Biophysics
[4] University of Southern California Keck School of Medicine,Department of Neuroscience
[5] Johns Hopkins University School of Medicine,undefined
来源
Nature Neuroscience | 2010年 / 13卷
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摘要
The intrinsically photosensitive melanopsin-expressing retinal ganglion neurons are important for nonvisual responses to light, such as circadian photoentrainment. These cells, however, require high light intensities to be activated and it has been unclear how photoentrainment to low light levels works. This study finds that rod photoreceptors are essential to photoentrainment at low and middle light intensities.
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页码:1107 / 1112
页数:5
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