The effect of hematopoietic stem cell transplantation on fertility and strategies for improvement

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作者
Brittany File
Mia Gergis
Usama Gergis
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[1] Thomas Jefferson University,Sidney Kimmel Medical College
[2] Tufts University,Department of Psychology
[3] Thomas Jefferson University,Department of Medical Oncology, Kimmel Cancer Center
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Ovarian dysfunction is an important consequence of hematopoietic stem cell transplantation (HCT). Premature ovarian failure and infertility can severely impact the quality of life for the increasing number of female long-term survivors of HCT. Here, we review the impact of HCT on ovarian function, post-transplant fertility and birth outcomes, and the contemporaneous strategies to preserve fertility for these patients.
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页码:1649 / 1656
页数:7
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