Anti-proliferative effects induced by anti-CD4 human/murine chimeric antibody and murine anti-CD4 monoclonal antibody

被引：1
|
作者：
Shen Guanxin
Zhu Huifen
Wang Xiaolin
Zhang Yue
Zhu Zhigang
Wang Shuo
机构：
[1] Tongji Medical University,Department of Immunology
[2] Wuhan Staff Medical College,Department of Pathophysiology
来源：
Journal of Tongji Medical University | 1999年 / 19卷 / 1期
关键词：
CD4 molecule; chimeric antibody; monoclonal antibody; inhibition of proliferation;
D O I：
10.1007/BF02895584
中图分类号：
学科分类号：
摘要：
The effects of chimeric anti-CD4 human/murine chimeric antibody and murine anti-CD4 monoclonal antibody (McAb) on the proliferation induced by anti-CD3 McAb, phytohemagglutinin (PHA), IL-2, and allogeneic cells were studied. The results showed that chimeric anti-CD4 antibody and murine anti-CD4 McAb could inhibit the proliferation induced by the above inducers and the inhibitory effects were related to the dosage of the antibodies.
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