Cannabinoids for the Treatment of Chronic Non-Cancer Pain: An Updated Systematic Review of Randomized Controlled Trials

被引：0
|
作者：
M. E. Lynch
Mark A. Ware
机构：
[1] Psychiatry and Pharmacology Dalhousie University,Departments of Anesthesiology, Pain Medicine and Perioperative Care
[2] McGill University,Departments of Anesthesia and Family Medicine
[3] Queen Elizabeth II Health Sciences Centre,Pain Management Unit
来源：
Journal of Neuroimmune Pharmacology | 2015年 / 10卷
关键词：
Cannabinoids; Chronic non-cancer pain; Neuropathic pain; Systematic review; Marijuana;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
An updated systematic review of randomized controlled trials examining cannabinoids in the treatment of chronic non-cancer pain was conducted according to PRISMA guidelines for systematic reviews reporting on health care outcomes. Eleven trials published since our last review met inclusion criteria. The quality of the trials was excellent. Seven of the trials demonstrated a significant analgesic effect. Several trials also demonstrated improvement in secondary outcomes (e.g., sleep, muscle stiffness and spasticity). Adverse effects most frequently reported such as fatigue and dizziness were mild to moderate in severity and generally well tolerated. This review adds further support that currently available cannabinoids are safe, modestly effective analgesics that provide a reasonable therapeutic option in the management of chronic non-cancer pain.
引用
收藏
页码：293 / 301
页数：8
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