Comparative Genomic Hybridization of Hepatocellular Carcinoma: Correlation With Fluorescence In Situ Hybridization in Paraffin-embedded Tissue

被引：0

作者：

Uma N. M. Rao

Susanne M. Gollin

Stacie Beaves

Kathleen Cieply

Michael Nalesnik

George K. Michalopoulos

机构：

[1] University of Pittsburgh Medical Center-Presbyterian University Hospital,Department of Pathology, Rm A610

[2] University of Pittsburgh Graduate School of Public Health and the Cytogenetics Facility,Department of Human Genetics

[3] University of Pittsburgh Center Institute,undefined

来源：

Molecular Diagnosis | 2001年 / 6卷 / 1期

关键词：

hepatocellular carcinoma; CGH; FISH;

D O I：

10.1007/BF03262101

中图分类号：

学科分类号：

摘要：

Background: Proto-oncogene MYC, mapped to chromosomal band 8q24 and the genes for hepatocyte growth factor (HGF at 7q21 ) and its receptor, MET, at chromosomal band 7q31, have an important role in the biology and growth of normal and neoplastic liver. Comparative genomic hybridization (CGH) and fluorescence in situ hybridization (FISH) studies have reported frequent abnormalities of chromosomes 1 and 8 in hepatocellular carcinomas (HCCs) of various clinical and pathological stages. Chromosome 7 involvement is reported to be less frequent.

引用

页码：27 / 37

页数：10

共 50 条

[1] Comparative genomic hybridization of hepatocellular carcinoma:: Correlation with fluorescence in situ hybridization in paraffin-embedded tissue
Rao, UNM
Gollin, SM
Beaves, S
Cieply, K
Nalesnik, M
Michalopoulos, GK
[J]. MOLECULAR DIAGNOSIS, 2001, 6 (01): : 27 - 37
[2] Fluorescence in situ hybridization on formalin-fixed and paraffin-embedded tissue
Petersen, BL
Sorensen, MC
Pedersen, S
Rasmussen, M
[J]. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 2004, 12 (03) : 259 - 265
[3] Cytogenetical diagnosis in paraffin-embedded fetoplacental tissue using comparative genomic hybridization
Ozcan, T
Burki, N
Parkash, V
Huang, XH
Pejovic, T
Mahoney, MJ
Ward, DC
[J]. PRENATAL DIAGNOSIS, 2000, 20 (01) : 41 - 44
[4] Glioma test array for use with formalin-fixed, paraffin-embedded tissue: array comparative genomic hybridization correlates with loss of heterozygosity and fluorescence in situ hybridization
Mohapatra, Gayatry
Betensky, Rebecca A.
Miller, Ezra R.
Carey, Bjorn
Gaumont, Leah D.
Engler, David A.
Louis, David N.
[J]. CANCER RESEARCH, 2006, 66 (08)
[5] Glioma test array for use with formalin-fixed, paraffin-embedded tissue - Array comparative genomic hybridization correlates with loss of heterozygosity and fluorescence in situ hybridization
Mohapatra, Gayatry
Betensky, Rebecca A.
Miller, Ezra R.
Carey, Bjorn
Gaumont, Leah D.
Engler, David A.
Louis, David N.
[J]. JOURNAL OF MOLECULAR DIAGNOSTICS, 2006, 8 (02): : 268 - 276
[6] The use of fluorescence in situ hybridization (FISH) on paraffin-embedded tissue sections for the study of microchimerism
Johnson, KL
Zhen, DK
Bianchi, DW
[J]. BIOTECHNIQUES, 2000, 29 (06) : 1220 - +
[7] DETECTION OF THE PHILADELPHIA-CHROMOSOME IN PARAFFIN-EMBEDDED TISSUE BY FLUORESCENCE IN-SITU HYBRIDIZATION
BRYNES, RK
MCCOURTY, A
HO, JP
TRAWEEK, ST
SNYDER, DS
SLOVAK, ML
[J]. MODERN PATHOLOGY, 1994, 7 (05) : 565 - 569
[8] Fluorescence in situ hybridization on nuclei from paraffin-embedded tissue in low stage pure embryonal carcinoma of the testis
Blough, RI
Heerema, NA
Albers, P
Foster, RS
[J]. JOURNAL OF UROLOGY, 1998, 159 (01): : 240 - 244
[9] Fluorescence In Situ Hybridization Study of Chromosome Abnormalities of Upper Urinary Tract Urothelial Carcinoma in Paraffin-Embedded Tissue
Bing, Zhanyong
Li, Jinhong
Master, Stephen R.
Lee, Chyi-chia
Puthiyaveettil, Raghunath
Tomaszewski, John E.
[J]. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2012, 138 (03) : 382 - 389
[10] Chromosomal abnormalities in renal cell carcinoma variants detected by Urovysion fluorescence in situ hybridization on paraffin-embedded tissue
Reid-Nicholson, Michelle D.
Motiwala, Nisrin
Drury, Scott C.
Peiper, Stephen C.
Terris, Martha K.
Waller, Jennifer L.
Ramalingam, Preetha
[J]. ANNALS OF DIAGNOSTIC PATHOLOGY, 2011, 15 (01) : 37 - 45

← 1 2 3 4 5 →