Putative novel outer membrane antigens multi-epitope DNA vaccine candidates identified by Immunoinformatic approaches to control Acinetobacter baumannii

被引：0
|
作者：
Niloofar Sadat Tabibpour
Abbas Doosti
Ali Sharifzadeh
机构：
[1] Islamic Azad University,Department of Biology, Faculty of Basic Sciences, Shahrekord Branch
[2] Islamic Azad University,Biotechnology Research Center, Shahrekord Branch
[3] Islamic Azad University,Department of Microbiology, Faculty of Veterinary Medicine
来源：
BMC Immunology | / 24卷
关键词：
Multi-epitope polypeptide; Reverse vaccinology; Acinetobacter baumannii;
D O I：
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学科分类号：
摘要：
Multi-epitope polypeptide vaccines, a fusion protein, often have a string-of-beads system composed of various specific peptide epitopes, potential adjuvants, and linkers. When choosing the sequence of various segments and linkers, many alternatives are available. These variables can influence the vaccine’s effectiveness through their effects on physicochemical properties and polypeptide tertiary structure.
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