Ceftaroline fosamil: a guide to its use in complicated skin and soft tissue infections and community-acquired pneumonia in the EU

Ceftaroline fosamil (Zinforo™; Teflaro®), the prodrug of ceftaroline, is an advanced-generation, parenteral cephalosporin with a broad spectrum of activity against clinically relevant Gram-positive and Gram-negative organisms. In clinical trials, intravenous ceftaroline fosamil was an effective and generally well tolerated treatment in hospitalized patients with complicated skin and soft tissue infections (noninferior to intravenous vancomycin plus aztreonam) or hospitalized community-acquired pneumonia (superior to intravenous ceftriaxone). © 2014, Springer International Publishing Switzerland.