FAK inhibition radiosensitizes pancreatic ductal adenocarcinoma cells in vitro

被引:0
|
作者
A. Allam Mohamed
Andreas Thomsen
Marie Follo
Costantinos Zamboglou
Peter Bronsert
Hanan Mostafa
Aber Amen
Mohamed Mekawy
Anca L. Grosu
Thomas B. Brunner
机构
[1] University of Freiburg,Department of Radiation Oncology, Medical Center, Faculty of Medicine
[2] University of Freiburg,Department of Medicine I, Medical Center, Faculty of Medicine
[3] University of Freiburg,Institute for Surgical Pathology, Medical Center, Faculty of Medicine
[4] Assiut University Hospitals,Clinical Oncology and Nuclear Medicine Department
[5] German Cancer Consortium (DKTK),Partner Site Freiburg
[6] RWTH Aachen University,Department of Radiation Oncology
[7] University of Magdeburg,Department of Radiation Oncology
来源
关键词
Pancreatic ductal adenocarcinoma; Focal adhesion kinase; Radiosensitization; Pancreatic stellate cell; Microenvironment; Stroma;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:27 / 38
页数:11
相关论文
共 50 条
  • [1] FAK inhibition radiosensitizes pancreatic ductal adenocarcinoma cells in vitro
    Mohamed, A. Allam
    Thomsen, Andreas
    Follo, Marie
    Zamboglou, Costantinos
    Bronsert, Peter
    Mostafa, Hanan
    Amen, Aber
    Mekawy, Mohamed
    Grosu, Anca L.
    Brunner, Thomas B.
    STRAHLENTHERAPIE UND ONKOLOGIE, 2021, 197 (01) : 27 - 38
  • [2] Targeting one-carbon metabolism radiosensitizes pancreatic ductal adenocarcinoma cells (PDAC)
    Nenwani, Minal
    Achreja, Abhinav
    Animasahun, Olamide
    Sarangi, Itisam
    Roy, Jyotirmoy
    Choppara, Srinadh
    Wuchu, Fulei
    Paserba, Miya
    Mittal, Anjali
    Quispe, Sergio
    Mohan, Aradhana
    Morgan, Meredith
    Lawrence, Theodore S.
    Nagrath, Deepak
    CANCER RESEARCH, 2023, 83 (07)
  • [3] Inhibition of the Hedgehog pathway induces autophagy in pancreatic ductal adenocarcinoma cells
    Xu, Yonghua
    An, Yong
    Wang, Xuehao
    Zha, Wenzhang
    Li, Xiangcheng
    ONCOLOGY REPORTS, 2014, 31 (02) : 707 - 712
  • [4] Inhibition of focal adhesion kinase (FAK) improves pancreatic ductal adenocarcinoma's response to immunotherapy by targeting cancer stem cells (CSCs).
    Zhu, Yezi
    Sandow, Lyndsey
    Matsui, William
    CANCER RESEARCH, 2021, 81 (22)
  • [5] Mast cells in pancreatic ductal adenocarcinoma
    Chang, David Z.
    ONCOIMMUNOLOGY, 2012, 1 (05): : 754 - 755
  • [6] In Vitro Selective Suppression of Tumor Cells by an Oncolytic Peptide in Pancreatic Ductal Adenocarcinoma
    Rashid, Khalid
    Ahmad, Aqeel
    INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS, 2021, 27 (02) : 863 - 873
  • [7] In Vitro Selective Suppression of Tumor Cells by an Oncolytic Peptide in Pancreatic Ductal Adenocarcinoma
    Khalid Rashid
    Aqeel Ahmad
    International Journal of Peptide Research and Therapeutics, 2021, 27 : 863 - 873
  • [8] In vitro Radiosensitization Effect of FAK inhibition in Pancreatic Cancer
    Allam, A.
    Thomsen, A.
    Follo, M.
    Mekawy, M.
    Mostafa, H.
    Amen, A.
    Brunner, T.
    STRAHLENTHERAPIE UND ONKOLOGIE, 2018, 194 : S13 - S13
  • [9] Galectin-1 Secreted by Activated Stellate Cells in Pancreatic Ductal Adenocarcinoma Stroma Promotes Proliferation and Invasion of Pancreatic Cancer Cells An In Vitro Study on the Microenvironment of Pancreatic Ductal Adenocarcinoma
    Xue, Xiaofeng
    Lu, Zipeng
    Tang, Dong
    Yao, Jie
    An, Yong
    Wu, Junli
    Li, Qiang
    Gao, Wentao
    Xu, Zekuan
    Qian, Zhuyin
    Dai, Cuncai
    Wei, Jishu
    Miao, Yi
    Jiang, Kuirong
    PANCREAS, 2011, 40 (06) : 832 - 839
  • [10] Immunophenotypes of Ductal Epithelial Cells in Advanced Pancreatic Ductal Adenocarcinoma
    Zhou, Rui
    Xu, Xiaoxiao
    Liu, Meizhen
    Wu, Xinmou
    Li, Rong
    DIGESTION, 2019, 99 (03) : 247 - 251