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Univ Pavia, Ist Ricovero & Cura Carattere Sci IRCCS Policlin, Amyloidosis Res & Treatment Ctr Fdn, Dept Mol Med, Viale Golgi,19 IT, I-27100 Pavia, Italy Tufts Med Ctr, Div Hematol Oncol, 800 Washington St, Boston, MA 02111 USA