Biotechnology and bioremediation: successes and limitations

被引:0
|
作者
M. Dua
A. Singh
N. Sethunathan
A. Johri
机构
[1] Department of Zoology,
[2] University of Delhi,undefined
[3] Delhi 110007,undefined
[4] India,undefined
[5] Department of Biology,undefined
[6] University of Waterloo,undefined
[7] Waterloo,undefined
[8] N2L 3G1,undefined
[9] Ontario,undefined
[10] Canada,undefined
[11] CSIRO Land and Water,undefined
[12] PMB 2,undefined
[13] Glen Osmond,undefined
[14] SA 5064,undefined
[15] Australia,undefined
[16] Present address: Channing Laboratory,undefined
[17] Harvard Medical School,undefined
[18] 181 Longwood Avenue,undefined
[19] Boston,undefined
[20] MA 02115,undefined
[21] USA,undefined
[22] Present address: Department of Biomedical Research,undefined
[23] Division of Hematology/Oncology,undefined
[24] St. Elizabeth Medical Center,undefined
[25] School of Medicine,undefined
[26] Tufts University,undefined
[27] Boston,undefined
[28] MA 02135,undefined
[29] USA,undefined
来源
关键词
Toxicity; Petroleum; Hydrocarbon; Polycyclic Aromatic Hydrocarbon; Biodegradation;
D O I
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学科分类号
摘要
With advances in biotechnology, bioremediation has become one of the most rapidly developing fields of environmental restoration, utilizing microorganisms to reduce the concentration and toxicity of various chemical pollutants, such as petroleum hydrocarbons, polycyclic aromatic hydrocarbons, polychlorinated biphenyls, phthalate esters, nitroaromatic compounds, industrial solvents, pesticides and metals. A number of bioremediation strategies have been developed to treat contaminated wastes and sites. Selecting the most appropriate strategy to treat a specific site can be guided by considering three basic principles: the amenability of the pollutant to biological transformation to less toxic products (biochemistry), the accessibility of the contaminant to microorganisms (bioavailability) and the opportunity for optimization of biological activity (bioactivity). Recent advances in the molecular genetics of biodegradation and studies on enzyme-tailoring and DNA-shuffling are discussed in this paper.
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页码:143 / 152
页数:9
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