Is Asthma an Infectious Disease? New Evidence

被引:0
|
作者
T. Prescott Atkinson
机构
[1] Children’s of Alabama CPP M220,
来源
关键词
Asthma; Infection; Respiratory syncytial virus; Rhinovirus; Virus; Microbiome; Infectious disease; Viral infections; Pathogenesis; Antibiotics;
D O I
暂无
中图分类号
学科分类号
摘要
The pathogenetic mechanisms leading to asthma are likely to be diverse, influenced by multiple genetic polymorphisms as well as elements of the environment. Recent data on the microbiome of the airway have revealed intriguing differences between the number and diversity of microbial populations in healthy persons and asthmatics. There is convincing evidence that early viral infections, particularly with human rhinovirus and respiratory syncytial virus, are often associated with the development of chronic asthma and with exacerbations. Recent studies suggest that two unrelated types of atypical bacteria, Mycoplasma pneumoniae (Mpn) and Chlamydia pneumoniae, are present in the airways of a substantial proportion of the population, bringing up the possibility that the persistent presence of the organism may contribute to the asthmatic phenotype in a subset of patients. This review will examine the current data regarding a possible role for infection in chronic asthma with a particular focus on atypical bacterial infections.
引用
收藏
页码:702 / 709
页数:7
相关论文
共 50 条
  • [1] Is Asthma an Infectious Disease? New Evidence
    Atkinson, T. Prescott
    [J]. CURRENT ALLERGY AND ASTHMA REPORTS, 2013, 13 (06) : 702 - 709
  • [2] Asthma: A Chronic Infectious Disease?
    Caramori, Gaetano
    Papadopoulos, Nikos
    Contoli, Marco
    Marku, Brunilda
    Forini, Giacomo
    Pauletti, Alessia
    Johnston, Sebastian L.
    Papi, Alberto
    [J]. CLINICS IN CHEST MEDICINE, 2012, 33 (03) : 473 - +
  • [3] Clinical evidence - Infectious disease: diarrhea
    de Bruyn, G
    [J]. WESTERN JOURNAL OF MEDICINE, 2000, 172 (06): : 409 - 412
  • [4] Is asthma an infectious disease? Thomas A. Neff lecture
    Lemanske, RF
    [J]. CHEST, 2003, 123 (03) : 385S - 390S
  • [5] New evidence of inflammation in asthma
    Vignola, AM
    Gagliardo, R
    Guerrera, D
    Chiappara, G
    Chanez, P
    Bousquet, J
    Bonsignore, G
    [J]. THORAX, 2000, 55 : S59 - S60
  • [6] New additions to Infectious Disease
    Smith D.
    [J]. Critical Care, 3 (1):
  • [7] INFECTIOUS ASTHMA, BACTERIAL ASTHMA
    DUBOISDEMONTREYNAUD, JM
    [J]. REVUE FRANCAISE D ALLERGOLOGIE ET D IMMUNOLOGIE CLINIQUE, 1979, 19 (03): : 159 - 159
  • [8] INFECTIOUS ASTHMA
    COLEMAN, WP
    [J]. SOUTHERN MEDICAL JOURNAL, 1969, 62 (10) : 1275 - &
  • [9] INFECTIOUS ASTHMA
    COLEMAN, WP
    [J]. SOUTHERN MEDICAL JOURNAL, 1970, 63 (07) : 800 - +
  • [10] Infectious asthma"
    Thomas, WS
    [J]. JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1931, 97 : 0124 - 0124