Mild traumatic brain injury (TBI) is defined as a head trauma resulting in a brief loss of consciousness and/or alteration of mental state. Diagnostic methods to determine the extent of injury to the brain and potential long-term damage in patients are lacking. In this Review, the authors discuss the need for fluid biomarkers of mild TBI, and the potential validation of biomarkers before clinical implementation.
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Cent Queensland Univ, Sch Hlth Med & Appl Sci, Bldg 7, Rockhampton, Qld 4701, AustraliaCent Queensland Univ, Sch Hlth Med & Appl Sci, Bldg 7, Rockhampton, Qld 4701, Australia
Hiskens, Matthew I.
Schneiders, Anthony G.
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Cent Queensland Univ, Sch Hlth Med & Appl Sci, Bldg 7, Rockhampton, Qld 4701, AustraliaCent Queensland Univ, Sch Hlth Med & Appl Sci, Bldg 7, Rockhampton, Qld 4701, Australia
Schneiders, Anthony G.
Angoa-Perez, Mariana
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John D Dingell VA Med Ctr, Res & Dev Serv, Detroit, MI USA
Wayne State Univ, Sch Med, Dept Psychiat & Behav Neurosci, Detroit, MI USACent Queensland Univ, Sch Hlth Med & Appl Sci, Bldg 7, Rockhampton, Qld 4701, Australia
Angoa-Perez, Mariana
Vella, Rebecca K.
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Cent Queensland Univ, Sch Hlth Med & Appl Sci, Bldg 7, Rockhampton, Qld 4701, AustraliaCent Queensland Univ, Sch Hlth Med & Appl Sci, Bldg 7, Rockhampton, Qld 4701, Australia
Vella, Rebecca K.
Fenning, Andrew S.
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Cent Queensland Univ, Sch Hlth Med & Appl Sci, Bldg 7, Rockhampton, Qld 4701, AustraliaCent Queensland Univ, Sch Hlth Med & Appl Sci, Bldg 7, Rockhampton, Qld 4701, Australia
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Boston Childrens Hosp, Div Emergency Med, 300 Longwood Ave, Boston, MA 02115 USABoston Childrens Hosp, Div Emergency Med, 300 Longwood Ave, Boston, MA 02115 USA
Mannix, Rebekah
Levy, Rachel
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Med Coll Georgia, Augusta, GA 30912 USABoston Childrens Hosp, Div Emergency Med, 300 Longwood Ave, Boston, MA 02115 USA
Levy, Rachel
Zemek, Roger
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Univ Ottawa, Dept Pediat, Ottawa, ON, Canada
Univ Ottawa, Dept Emergency Med, Ottawa, ON, Canada
Childrens Hosp, Eastern Ontario Res Inst, Ottawa, ON, CanadaBoston Childrens Hosp, Div Emergency Med, 300 Longwood Ave, Boston, MA 02115 USA
Zemek, Roger
Yeates, Keith Owen
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Univ Calgary, Alberta Childrens Hosp, Res Inst, Dept Psychol, Calgary, AB, Canada
Univ Calgary, Hotchkiss Brain Inst, Calgary, AB, CanadaBoston Childrens Hosp, Div Emergency Med, 300 Longwood Ave, Boston, MA 02115 USA
Yeates, Keith Owen
Arbogast, Kristy
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Univ Penn, Perelman Sch Med, Childrens Hosp Philadelphia, Div Emergency Med, Philadelphia, PA 19104 USABoston Childrens Hosp, Div Emergency Med, 300 Longwood Ave, Boston, MA 02115 USA
Arbogast, Kristy
Meehan, William P.
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Boston Childrens Hosp, Div Sports Med, Micheli Ctr Sports Injury Prevent, Boston, MA USA
Boston Childrens Hosp, Dept Pediat, Boston, MA USABoston Childrens Hosp, Div Emergency Med, 300 Longwood Ave, Boston, MA 02115 USA
Meehan, William P.
Leddy, John
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SUNY Buffalo, UBMD Dept Orthoped & Sports Med, Buffalo, NY USABoston Childrens Hosp, Div Emergency Med, 300 Longwood Ave, Boston, MA 02115 USA
Leddy, John
Master, Christina
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Univ Penn, Perelman Sch Med, Childrens Hosp Philadelphia, Sports Med & Performance,Ctr Ctr Injury Res & Pre, Philadelphia, PA 19104 USABoston Childrens Hosp, Div Emergency Med, 300 Longwood Ave, Boston, MA 02115 USA
Master, Christina
Mayer, Andrew R.
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Univ New Mexico, Mind Res Network, LBERI, Albuquerque, NM 87131 USA
Univ New Mexico, Dept Psychol, Albuquerque, NM 87131 USA
Univ New Mexico, Dept Neurol, Albuquerque, NM 87131 USA
Univ New Mexico, Dept Psychiat, Albuquerque, NM 87131 USABoston Childrens Hosp, Div Emergency Med, 300 Longwood Ave, Boston, MA 02115 USA
Mayer, Andrew R.
Howell, David R.
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Univ Colorado, Sch Med, Childrens Hosp, Colorado Sports Med Ctr, Aurora, CO USA
Univ Colorado, Sch Med, Dept Orthoped, Aurora, CO USABoston Childrens Hosp, Div Emergency Med, 300 Longwood Ave, Boston, MA 02115 USA
Howell, David R.
Meier, Timothy B.
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Med Coll Wisconsin, Dept Neurosurg, Milwaukee, WI 53226 USA
Med Coll Wisconsin, Dept Cell Biol, Milwaukee, WI 53226 USA
Med Coll Wisconsin, Dept Neurobiol & Anat, Milwaukee, WI 53226 USA
Med Coll Wisconsin, Dept Biomed Engn, Milwaukee, WI 53226 USABoston Childrens Hosp, Div Emergency Med, 300 Longwood Ave, Boston, MA 02115 USA