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Dopamine-Induced Apoptosis Is Inhibited in PC12 Cells Expressing Bcl-2

被引：0
|
作者：
D. Offen
I. Ziv
H. Panet
L. Wasserman
R. Stein
E. Melamed
A. Barzilai
机构：
[1] Department of Neurology,Department of Biochemistry, G. Wise Faculty of Life Sciences
[2] Beilinson Medical Center,Department of Neurology
[3] and Tel Aviv University Sackler Medical School,undefined
[4] Felsenstein Medical Research Center,undefined
[5] Beilinson Medical Center,undefined
[6] and Tel Aviv University Sackler Medical School,undefined
[7] Tel-Aviv University,undefined
[8] Rabin Medical Center,undefined
来源：
Cellular and Molecular Neurobiology | 1997年 / 17卷
关键词：
Parkinson's disease; dopamine; dopamine-melanin; apoptosis; bcl-2; antioxidants;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
1. Degeneration of nigrostriatal dopaminergic neurons is the major pathogenic substrate of Parkinson's disease (PD). It is assumed that the lethal trigger is the accumulation of oxidative reactive species generated during metabolism of the natural neurotransmitter dopamine.
引用
收藏
页码：289 / 304
页数：15
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