TNFα reverse signaling promotes sympathetic axon growth and target innervation

被引：0
|
作者：
Lilian Kisiswa
Catarina Osório
Clara Erice
Thomas Vizard
Sean Wyatt
Alun M Davies
机构：
[1] School of Biosciences,Division of Molecular Biosciences
[2] Cardiff University,undefined
[3] Present address: Nuffield Department of Clinical Neurosciences,undefined
[4] John Radcliffe Hospital,undefined
[5] Oxford,undefined
[6] UK.,undefined
来源：
Nature Neuroscience | 2013年 / 16卷
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学科分类号：
摘要：
The authors show that the TNFα receptor, expressed on peripheral target tissue, can act as a ligand to induce reverse TNFα signaling in superior cervical ganglion neurons, promoting neurite growth and branching. This reverse signaling is crucial in establishing sympathetic innervation.
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页码：865 / 873
页数：8
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