Sleep and Psychiatric Disorders in Persons With Mild Traumatic Brain Injury

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作者
Tatyana Mollayeva
Andrea D’Souza
Shirin Mollayeva
机构
[1] University of Toronto,Rehabilitation Sciences Institute, Faculty of Medicine
[2] Toronto Rehabilitation Institute-University Health Network,Acquired Brain Injury Research Lab
[3] University of Toronto,Faculty of Arts and Science
[4] University of Toronto Mississauga,undefined
[5] Graduate Biology Department University of Toronto Mississauga,undefined
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关键词
Mild traumatic brain injury; Sleep-wake cycle; Risk; Sleep disorders; Psychopathology; Comorbidity;
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摘要
Mild traumatic brain injury (mTBI) frequently challenges the integrity of sleep function by affecting multiple brain areas implicated in controlling the switch between wakefulness and sleep and those involved in circadian and homeostatic processes; the malfunction of each causes a variety of disorders. In this review, we discuss recent data on the dynamics between disorders of sleep and mental/psychiatric disorders in persons with mTBI. This analysis sets the stage for understanding how a variety of physiological, emotional and environmental influences affect sleep and mental activities after injury to the brain. Consideration of the intricate links between sleep and mental functions in future research can increase understanding on the underlying mechanisms of sleep-related and psychiatric comorbidity in mTBI.
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