Exhaled nitric oxide and clinical phenotypes of childhood asthma

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作者
Bruno Mahut
Séverine Peyrard
Christophe Delclaux
机构
[1] Cabinet La Berma,Assistance Publique
[2] Service de Physiologie - Clinique de la Dyspnée,Hôpitaux de Paris; Hôpital Européen Georges Pompidou
[3] Mosquito respiratory research group,CIC 9201 Plurithématique
[4] University Paris Descartes,undefined
[5] Hôpital Européen Georges Pompidou,undefined
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Nitric Oxide; Asthma; Asthma Control; Asthmatic Child; Tobacco Exposure;
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摘要
Whether exhaled NO helps to identify a specific phenotype of asthmatic patients remains debated. Our aims were to evaluate whether exhaled NO (FENO0.05) is independently associated (1) with underlying pathophysiological characteristics of asthma such as airway tone (bronchodilator response) and airway inflammation (inhaled corticosteroid [ICS]-dependant inflammation), and (2) with clinical phenotypes of asthma.
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