Modulation of Antagonist Binding to Serotonin1A Receptors from Bovine Hippocampus by Metal Ions

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作者
K. G. Harikumar
Amitabha Chattopadhyay
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[1] Centre for Cellular and Molecular Biology,
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5-HT; receptors; -MPPI; -MPPF; metal ions; Scatchard analysis; bovine hippocampus;
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摘要
1. The serotonin1A(5-HT1A) receptors are members of a superfamily of seven transmembrane domain receptors that couple to G-proteins. They appear to be involved in various behavioral and cognitive functions. Although specific 5-HT1Aagonists have been discovered more than a decade back, the development of selective 5-HT1Aantagonists has been achieved only recently.
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页码:453 / 464
页数:11
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