Frequency of West Nile Virus Infection in Iranian Blood Donors

被引:0
|
作者
Afsaneh Aghaie
John Aaskov
Sadegh Chinikar
Matthias Niedrig
Soudabeh Banazadeh
Hashem Khorsand Mohammadpour
机构
[1] High Institute for Research and Education in Transfusion Medicine,Blood Transfusion Research Center
[2] Queensland University of Technology,Arboviruses and VHFs Lab
[3] Pasteur Institute of Iran,Quality Assurance
[4] Robert Koch Institute,Research Center
[5] Iranian Blood Research and Fractionation Holding Company,undefined
[6] Iranian Blood Research and Fractionation Holding Company,undefined
关键词
West Nile virus ; WNV); Blood donor; Iran; Donor selection; Epidemiology; Enzyme linked immune sorbent assay (ELISA); Immunoflouorescence assay (IFA);
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摘要
West Nile virus (WNV) can be transmitted by blood transfusions and organ transplants. This study was a retrospective study which was performed in Blood Transfusion Center to evaluate the WNV infection in blood donors in Iran. A total of 540 blood samples were taken from volunteer healthy donors who referred for blood donation to Chabahar Blood Center. The presence of WNV was studied by detecting immunoglobulin G (IgG) WNV by enzyme linked immune sorbent assay (ELISA). Demonstration of elevated WNV IgG confirmed by immunoflouorescence assay (IFA) Euroimmun kit. Out of the 540 samples 17.96 % (97 cases) were seropositive by ELISA and 1.48 % (8 cases) was seropositive by IFA. This means that 8.24 % of ELISA seropositive samples were confirmed by IFA. Special attention should be paid to criteria of donor selection, albeit positive results may be due to a previous infection in these donors.
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页码:343 / 346
页数:3
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