Matrine suppresses proliferation and induces apoptosis in human cholangiocarcinoma cells through suppression of JAK2/STAT3 signaling

被引:0
|
作者
Nanmu Yang
Feng Han
Hong Cui
Jinxi Huang
Tao Wang
Yi Zhou
Jinxue Zhou
机构
[1] The Affiliated Tumor Hospital of Zhengzhou University,Department of Hepatopancreatobiliary Surgery
[2] Henan Cancer Hospital,Department of Anesthesia
[3] The Third Affiliated Hospital of Zhengzhou University,undefined
来源
Pharmacological Reports | 2015年 / 67卷
关键词
Apoptosis; Mcl-1; Phytochemical; STAT3 signaling; Therapy;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:388 / 393
页数:5
相关论文
共 50 条
  • [1] Matrine suppresses proliferation and induces apoptosis in human cholangiocarcinoma cells through suppression of JAK2/STAT3 signaling
    Yang, Nanmu
    Han, Feng
    Cui, Hong
    Huang, Jinxi
    Wang, Tao
    Zhou, Yi
    Zhou, Jinxue
    [J]. PHARMACOLOGICAL REPORTS, 2015, 67 (02) : 388 - 393
  • [2] Bigelovin inhibits STAT3 signaling by inactivating JAK2 and induces apoptosis in human cancer cells
    Hao-hao Zhang
    Shan Kuang
    Ying Wang
    Xiao-xiao Sun
    Yuan Gu
    Li-hong Hu
    Qiang Yu
    [J]. Acta Pharmacologica Sinica, 2015, 36 : 507 - 516
  • [3] Bigelovin inhibits STAT3 signaling by inactivating JAK2 and induces apoptosis in human cancer cells
    Zhang, Hao-hao
    Kuang, Shan
    Wang, Ying
    Sun, Xiao-xiao
    Gu, Yuan
    Hu, Li-hong
    Yu, Qiang
    [J]. ACTA PHARMACOLOGICA SINICA, 2015, 36 (04) : 507 - 516
  • [4] Novel JAK2 inhibitor blocks STAT3 and MAPK signaling pathways, inhibits proliferation and induces apoptosis of human myeloma cells
    Scuto, Anna
    Wu, Jun
    Wang, Yan
    Kretzner, Leo
    Yen, Yun
    Zinda, Michael
    Huszar, Dennis
    Jove, Richard
    [J]. CANCER RESEARCH, 2009, 69
  • [5] Celastrol Suppresses Growth and Induces Apoptosis of Human Hepatocellular Carcinoma through the Modulation of STAT3/JAK2 Signaling Cascade In Vitro and In Vivo
    Rajendran, Peramaiyan
    Li, Feng
    Shanmugam, Muthu K.
    Kannaiyan, Radhamani
    Goh, Jen Nee
    Wong, Kwong Fai
    Wang, Wei
    Khin, Ester
    Tergaonkar, Vinay
    Kumar, Alan Prem
    Luk, John M.
    Sethi, Gautam
    [J]. CANCER PREVENTION RESEARCH, 2012, 5 (04) : 631 - 643
  • [6] Atractylenolide I Induces Apoptosis and Suppresses Glycolysis by Blocking the JAK2/STAT3 Signaling Pathway in Colorectal Cancer Cells
    Li, Yanxi
    Wang, Yongpeng
    Liu, Zhexian
    Guo, Xingqi
    Miao, Ziwei
    Ma, Siping
    [J]. FRONTIERS IN PHARMACOLOGY, 2020, 11
  • [7] RLIP depletion induces apoptosis associated with inhibition of JAK2/STAT3 signaling in melanoma cells
    Singhal, Sharad S.
    Mohanty, Atish
    Kulkarni, Prakash
    Horne, David
    Awasthi, Sanjay
    Salgia, Ravi
    [J]. CARCINOGENESIS, 2021, 42 (05) : 742 - 752
  • [8] Daidzin inhibits growth and induces apoptosis through the JAK2/STAT3 in human cervical cancer HeLa cells
    Yao, Zhilin
    Xu, Xiaojuan
    Huang, Yinghong
    [J]. SAUDI JOURNAL OF BIOLOGICAL SCIENCES, 2021, 28 (12) : 7077 - 7081
  • [9] Thymoquinone induces oxidative stress-mediated apoptosis through downregulation of Jak2/STAT3 signaling pathway in human melanoma cells
    Raut, Pawan Kumar
    Lee, Hui Seong
    Joo, Sang Hoon
    Chun, Kyung-Soo
    [J]. FOOD AND CHEMICAL TOXICOLOGY, 2021, 157
  • [10] Thymoquinone induces apoptosis through inhibition of JAK2/STAT3 signaling via production of ROS in human renal cancer Caki cells
    Chae, In Gyeong
    Chun, Kyung-Soo
    [J]. CANCER RESEARCH, 2016, 76