SuReSim: Simulating localization microscopy experiments from ground truth models

被引：0
|
作者：
Venkataramani V. [1 ]
Herrmannsdörfer F. [1 ]
Heilemann M. [1 ,2 ]
Kuner T. [1 ]
机构：
[1] Institute for Anatomy and Cell Biology, Heidelberg University, Heidelberg
[2] Institute for Physical and Theoretical Chemistry, Goethe-University Frankfurt, Frankfurt
来源：
Nature Methods | 2016年 / 13卷 / 4期
关键词：
D O I：
10.1038/nmeth.3775
中图分类号：
学科分类号：
摘要：
Super-resolution fluorescence microscopy has become a widely used tool in many areas of research. However, designing and validating super-resolution experiments to address a research question in a technically feasible and scientifically rigorous manner remains a fundamental challenge. We developed SuReSim, a software tool that simulates localization data of arbitrary three-dimensional structures represented by ground truth models, allowing users to systematically explore how changing experimental parameters can affect potential imaging outcomes. © 2016 Nature America, Inc. All rights reserved.
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收藏
页码：319 / 321
页数：2
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