Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus

被引：0

作者：

Kazuki Yasuda

Kazuaki Miyake

Yukio Horikawa

Kazuo Hara

Haruhiko Osawa

Hiroto Furuta

Yushi Hirota

Hiroyuki Mori

Anna Jonsson

Yoshifumi Sato

Kazuya Yamagata

Yoshinori Hinokio

He-Yao Wang

Toshihito Tanahashi

Naoto Nakamura

Yoshitomo Oka

Naoko Iwasaki

Yasuhiko Iwamoto

Yuichiro Yamada

Yutaka Seino

Hiroshi Maegawa

Atsunori Kashiwagi

Jun Takeda

Eiichi Maeda

Hyoung Doo Shin

Young Min Cho

Kyong Soo Park

Hong Kyu Lee

Maggie C Y Ng

Ronald C W Ma

Wing-Yee So

Juliana C N Chan

Valeriya Lyssenko

Tiinamaija Tuomi

Peter Nilsson

Leif Groop

Naoyuki Kamatani

Akihiro Sekine

Yusuke Nakamura

Ken Yamamoto

Teruhiko Yoshida

Katsushi Tokunaga

Mitsuo Itakura

Hideichi Makino

Kishio Nanjo

Takashi Kadowaki

Masato Kasuga

机构：

[1] Research Institute,Department of Metabolic Disorder

[2] International Medical Center of Japan,Division of Diabetes, Department of Internal Medicine

[3] Metabolism,Department of Diabetes and Endocrinology, Division of Molecule and Structure

[4] and Endocrinology,Department of Metabolic Diseases

[5] Kobe University Graduate School of Medicine,Department of Molecular and Genetic Medicine

[6] Gifu University School of Medicine,First Department of Medicine

[7] Graduate School of Medicine,Department of Clinical Sciences

[8] University of Tokyo,Department of Metabolic Medicine

[9] Ehime University Graduate School of Medicine,Division of Molecular Metabolism and Diabetes

[10] Wakayama Medical University,Division of Genetic Information

[11] Diabetes and Endocrinology,Department of Endocrinology and Metabolism

[12] University Hospital Malmö,Department of Medicine

[13] Lund University,Department of Diabetes and Clinical Nutrition

[14] Graduate School of Medicine,Division of Endocrinology and Metabolism, Department of Medicine

[15] Osaka University,Department of Genetic Epidemiology

[16] Tohoku University Graduate School of Medicine,Department of Internal Medicine

[17] Institute for Genome Research,Department of Medicine and Therapeutics

[18] University of Tokushima,Department of Medicine

[19] Kyoto Prefectural University of Medicine,Department of Clinical Sciences

[20] Graduate School of Medical Sciences,Division of Genomic Medicine, Department of Advanced Biomedical Engineering and Science

[21] Diabetes Center,Department of Molecular Genetics

[22] Tokyo Women's Medical University,Genetics Division

[23] Kyoto University School of Medicine,Department of Human Genetics

[24] Shiga University of Medical Science,undefined

[25] Clinical Genome Informatics Center,undefined

[26] Kobe University Graduate School of Medicine,undefined

[27] SNP Genetics Inc.,undefined

[28] Seoul National University College of Medicine,undefined

[29] The Chinese University of Hong Kong,undefined

[30] Shatin,undefined

[31] Helsinki University Hospital,undefined

[32] Folkhaelsan Research Center,undefined

[33] Medicine Research Unit,undefined

[34] University Hospital Malmö,undefined

[35] Lund University,undefined

[36] Tokyo Women's Medical University,undefined

[37] SNP Research Center,undefined

[38] Institute of Physical and Chemical Research (RIKEN),undefined

[39] Medical Institute of Bioregulation,undefined

[40] Kyushu University,undefined

[41] National Cancer Center Research Institute,undefined

[42] Graduate School of Medicine,undefined

[43] University of Tokyo,undefined

[44] Present addresses: Department of Medical Biochemistry,undefined

[45] Faculty of Medical and Pharmaceutical Sciences,undefined

[46] Kumamoto University,undefined

[47] Kumamoto 860-8556,undefined

[48] Japan (K. Yamagata),undefined

[49] Shanghai Institute of Materia Medica,undefined

[50] Chinese Academy of Science,undefined

来源：

Nature Genetics | 2008年 / 40卷

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摘要：

Masato Kasuga and colleagues and Shiro Maeda and colleagues each report the independent identification of SNPs in KCNQ1 associated with type 2 diabetes in the Japanese population. Each group replicated the associations in other populations of East Asian and European descent.

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页码：1092 / 1097

页数：5

共 50 条

[1] Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
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