Modulation of inflammatory signaling pathways by phytochemicals in ovarian cancer

被引：0
|
作者：
Mi-Kyung Kim
Kidong Kim
Jae Yong Han
Jeong Mook Lim
Yong Sang Song
机构：
[1] Seoul National University College of Medicine,Department of Obstetrics and Gynecology
[2] Korea Institute of Radiological and Medical Sciences,Department of Obstetrics and Gynecology, Korea Cancer Center Hospital
[3] Seoul National University,Major in Biomodulation, WCU and Department of Agricultural Biotechnology
[4] Seoul National University College of Medicine,Cancer Research Institute
来源：
Genes & Nutrition | 2011年 / 6卷
关键词：
Phytochemicals; Ovarian cancer; Anti-inflammation; Chemoprevention;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Inflammation has been suggested to be involved in cancer development and progression. Many clinical and experimental studies have shown that inflammation could contribute to ovarian carcinogenesis through activation of the NF-κB and AP-1 pathways by chronic inflammatory mediators. Phytochemicals, which are natural compounds derived from fruits and vegetables, have shown anti-inflammatory and anti-cancer effects. Due to their relatively low toxicity and easy accessibility, phytochemicals have been investigated for their chemopreventive potential against various cancers. In this review, we discuss the role of phytochemicals in preventing ovarian cancer through anti-inflammatory mechanisms.
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页码：109 / 115
页数：6
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